Small COPII coat GTPase SAR1 (SAR1) Recombinant Protein | SAR1 recombinant protein
Recombinant Cryptococcus neoformans var. neoformans serotype D Small COPII coat GTPase SAR1 (SAR1)
NCBI and Uniprot Product Information
Uniprot Description
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits ().
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Product Notes
The SAR1 sar1 (Catalog #AAA1172107) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-189aa; full length protein. The amino acid sequence is listed below: MFIINWFWDV LASLGLMNKS AKLLFLGLDN AGKTTLLHML KNDRLATLQP TLHPTSEELA IGNVKFTTYD LGGHIQARRL WRDYFPEVDG IVFLVDSADA ERFAESKAEL DSLLSIESLA QVPFLILGNK IDAYGAVSEE QLRHELGLYQ TTGKGKIPLR DIRPIEVFMC SVVMRQGYGE GFRWLSQYI. It is sometimes possible for the material contained within the vial of "Small COPII coat GTPase SAR1 (SAR1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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