ATP-dependent zinc metalloprotease YME1L1 (Yme1l1) Recombinant Protein | Yme1l1 recombinant protein

Recombinant Mouse ATP-dependent zinc metalloprotease YME1L1 (Yme1l1)

• Gene Names: Yme1l1; Ftsh; FtsH1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: ATP-dependent zinc metalloprotease YME1L1 (Yme1l1); Recombinant Mouse ATP-dependent zinc metalloprotease YME1L1 (Yme1l1); Recombinant ATP-dependent zinc metalloprotease YME1L1 (Yme1l1); ATP-dependent zinc metalloprotease YME1L1 EC= 3.4.24.-; ATP-dependent metalloprotease FtsH1 YME1-like protein 1; Yme1l1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-715
• Sequence: MFSLSSTVQPQVTIPLSHLINAFHSPKNISVSVNTPVSQKQHRDTVPEHEAPSSEPVLNLRDLGLSELKIGQIDKMVENLLPGFYKDKRVSSCWHTSHISAQSFFENKYGHLDMFSTLRSSSLYRQHPKTLRSICSDLQYFPVFIQSRGFKTLKSRTRRLQSTSERLVEAQNIAPSFVKGFLLRDRGTDLESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTVLGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDKSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILLRESYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR
• Sequence Length: 715

• Species: Mus musculus (Mouse)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 7305635
• NCBI GeneID: 27377
• NCBI Accession #: NP_038799.1
• NCBI GenBank Nucleotide #: NM_013771.5
• UniProt Accession #: O88967; Q7TNN5
• Molecular Weight: 80,028 Da
• NCBI Official Full Name: ATP-dependent zinc metalloprotease YME1L1
• NCBI Official Synonym Full Names: YME1-like 1 (S. cerevisiae)
• NCBI Official Symbol: Yme1l1
• NCBI Official Synonym Symbols: Ftsh; FtsH1
• NCBI Protein Information: ATP-dependent zinc metalloprotease YME1L1; YME1-like protein 1; ATP-dependent metalloprotease FtsH1
• UniProt Protein Name: ATP-dependent zinc metalloprotease YME1L1
• Protein Family: ATP-dependent zinc metalloprotease
• UniProt Gene Name: Yme1l1
• UniProt Entry Name: YMEL1_MOUSE

Uniprot Description

YME1L1: Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; EC 3.4.24.-; Protease

Cellular Component: membrane; mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: peptidase activity; hydrolase activity; metallopeptidase activity; metalloendopeptidase activity; metal ion binding; nucleotide binding; ATP binding

Biological Process: mitochondrion organization and biogenesis; cell proliferation; misfolded or incompletely synthesized protein catabolic process; proteolysis