AP-2 complex subunit mu (dpy-23) Recombinant Protein | dpy-23 recombinant protein
Recombinant Caenorhabditis elegans AP-2 complex subunit mu (dpy-23)
NCBI and Uniprot Product Information
Uniprot Description
Component of the adaptor complexes which link clathrin to receptors in coated vesicles (). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (). AP50 is a subunit of the plasma membrane adaptor (). Essential wnt/egl-20 signaling protein that functions in wnt/egl-20-producing cells (PubMed:18160346, PubMed:18160347). Required for the AP-2 complex-mediated endocytosis of membrane proteins including wntless homolog mig-14 in egl-20-producing cells (PubMed:18160346, PubMed:18160347). During development, regulates the migration of HSN neurons and the left and right Q neuroblasts (QL and QR, respectively) and their descendants, possibly through hox gene and wnt/egl-20 gene target mab-5, and plays a role in establishing ALM and PLM neuronal cell polarity (PubMed:18160346). Required for the asymmetric divisions of V5 cells (PubMed:18160346).
Research Articles on dpy-23
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Product Notes
The dpy-23 dpy-23 (Catalog #AAA1148880) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-441, Full length. The amino acid sequence is listed below: MIGGLFVYNH KGEVLISRIY RDDVTRNAVD AFRVNVIHAR QQVRSPVTNM ARTSFFHVKR GNVWICAVTR QNVNAAMVFE FLKRFADTMQ SYFGKLNEEN VKNNFVLIYE LLDEILDFGY PQNTDPGVLK TFITQQGVRT ADAPVPVTKE EQSQITSQVT GQIGWRREGI KYRRNELFLD VIEYVNLLMN QQGQVLSAHV AGKVAMKSYL SGMPECKFGI NDKITIEGKS KPGSDDPNKA SRAAVAIDDC QFHQCVKLTK FETEHAISFI PPDGEYELMR YRTTKDIQLP FRVIPLVREV SRNKMEVKVV VKSNFKPSLL AQKLEVRIPT PPNTSGVQLI CMKGKAKYKA GENAIVWKIK RMAGMKESQI SAEIDLLSTG NVEKKKWNRP PVSMNFEVPF APSGLKVRYL KVFEPKLNYS DHDVIKWVRY IGRSGLYETR C. It is sometimes possible for the material contained within the vial of "AP-2 complex subunit mu (dpy-23), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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