High osmolarity signaling protein SHO1 (SHO1) Recombinant Protein | SHO1 recombinant protein
Recombinant Saccharomyces cerevisiae High osmolarity signaling protein SHO1 (SHO1)
NCBI and Uniprot Product Information
Uniprot Description
Function: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane. PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures. Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress. Involved in the regulation of the mating pathway. May be a receptor that feeds into the pseudohyphal growth pathway
By similarity.
Subunit structure: Forms homooligomers
By similarity. Interacts (via the SH3 domain) with PBS2. Interacts with FUS1, STE11, STE50 and RNA polymerase II
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Bud
By similarity. Bud neck
By similarity. Cell projection
By similarity. Note: Localizes at the tip of the mating projection during conjugation
By similarity.
Sequence similarities: Belongs to the SHO1 family.Contains 1 SH3 domain.
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Product Notes
The High osmolarity signaling protein SHO1 (SHO1) sho1 (Catalog #AAA1140302) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-367. The amino acid sequence is listed below: MSISSKIRPT PRKPSRMATD HSFKMKNFYA DPFAISSISL AIVSWVIAIG GSISSASTNE SFPRFTWWGI VYQFLIICSL MLFYCFDLVD HYRIFITTSI AVAFVYNTNS ATNLVYADGP KKAAASAGVI LLSIINLIWI LYYGGDNASP TNRWIDSFSI KGIRPSPLEN SLHRARRRGN RNTTPYQNNV YNDAIRDSGY ATQFDGYPQQ QPSHTNYVSS TALAGFENTQ PNTSEAVNLH LNTLQQRINS ASNAKETNDN SNNQTNTNIG NTFDTDFSNG NTETTMGDTL GLYSDIGDDN FIYKAKALYP YDADDDDAYE ISFEQNEILQ VSDIEGRWWK ARRANGETGI IPSNYVQLID GPEEMHR. It is sometimes possible for the material contained within the vial of "High osmolarity signaling protein SHO1 (SHO1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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