RNA-dependent RNA polymerase 2 (RDR2) Recombinant Protein | RDR2 recombinant protein

Recombinant Arabidopsis thaliana RNA-dependent RNA polymerase 2 (RDR2) , partial

• Gene Names: RDR2; AtRDR2; RNA-dependent RNA polymerase 2; SILENCING MOVEMENT DEFICIENT 1; SMD1; T22B4.110; T22B4_110
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: RNA-dependent RNA polymerase 2 (RDR2); Recombinant Arabidopsis thaliana RNA-dependent RNA polymerase 2 (RDR2); partial; RDR2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1133

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 15237051
• NCBI GeneID: 826714
• NCBI Accession #: NP_192851.1
• NCBI GenBank Nucleotide #: NM_117183.3
• UniProt Accession #: O82504
• Molecular Weight: 129,325 Da
• NCBI Official Full Name: RNA-dependent RNA polymerase 2
• NCBI Official Symbol: RDR2
• NCBI Official Synonym Symbols: AtRDR2; RNA-dependent RNA polymerase 2; SILENCING MOVEMENT DEFICIENT 1; SMD1; T22B4.110; T22B4_110
• NCBI Protein Information: RNA-dependent RNA polymerase 2
• UniProt Protein Name: RNA-dependent RNA polymerase 2
• Protein Family: RNA-dependent RNA polymerase
• UniProt Gene Name: RDR2
• UniProt Synonym Gene Names: RDRP2; SMD1; AtRDRP2

NCBI Description

Encodes RNA-dependent RNA polymerase that is required for endogenous siRNA (but not miRNA) formation. Nomenclature according to Xie, et al. (2004).

Uniprot Description

RNA-dependent direct polymerase involved in the production of small interfering RNAs (siRNAs). Required for the biogenesis of endogenous siRNAs of 24 nucleotide which derive from heterochromatin and DNA repeats such as transposons or endogenous gene tandem repeats, such as repeats present in FWA gene. Involved in transcriptional gene silencing (TGS). Component of the RNA-directed DNA methylation (RdDM) silencing pathway that utilizes siRNAs to guide DNA methyltransferases to asymmetric cytosines. Involved in control of flowering time through RdDM of FWA locus. Required for reception of long-distance mRNA silencing in the shoot. Required for the formation of telomeric siRNAs and the RNA-dependent DNA methylation of asymmetric cytosines in telomeric (5'-CCCTAAA-3') repeats.