Sialidase-1 (NEU1) Recombinant Protein | NEU1 recombinant protein
Recombinant Bovine Sialidase-1 (NEU1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Sialidase-1 (NEU1); Recombinant Bovine Sialidase-1 (NEU1); NEU1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
48-415, Full length protein
Sequence
KDDFSLVHPLVTMEQLLWVSGKQIGSVDTFRIPLITTTPRGTLLAFAEARKMSTSDKGAKFIALRRSMDQGSTWSPTAFIVDDGETPDGLNLGAVVSDTTTGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSSPRNLSLDIGTEMFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGVSWRYGGGVSGIPYGQPKRENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIILRSYDACDTLRPRDVTFDTELVDPVVAAGAVATSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLTTLEGNVDGKDEAPQLYVLYEKGRNQYMESISLVKVSVYGTL
Sequence Length
368
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for NEU1 recombinant protein
This protein is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as protective protein ). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,433 Da
NCBI Official Full Name
sialidase-1
NCBI Official Synonym Full Names
neuraminidase 1
NCBI Official Symbol
NEU1
NCBI Protein Information
sialidase-1
UniProt Protein Name
Sialidase-1
Protein Family
UniProt Gene Name
NEU1
Uniprot Description
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage ().
Research Articles on NEU1
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Product Notes
The NEU1 neu1 (Catalog #AAA1115521) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 48-415, Full length protein. The amino acid sequence is listed below: KDDFSLVHPL VTMEQLLWVS GKQIGSVDTF RIPLITTTPR GTLLAFAEAR KMSTSDKGAK FIALRRSMDQ GSTWSPTAFI VDDGETPDGL NLGAVVSDTT TGVVFLFYSL CAHKAGCQVA STMLVWSKDD GVSWSSPRNL SLDIGTEMFA PGPGSGIQKQ REPRKGRLIV CGHGTLERDG VFCLLSDDHG VSWRYGGGVS GIPYGQPKRE NDFNPDECQP YELPDGSVVI NARNQNNYHC HCRIILRSYD ACDTLRPRDV TFDTELVDPV VAAGAVATSS GIVFFSNPAH PEFRVNLTLR WSFSNGTSWR KETVQLWPGP SGYSSLTTLE GNVDGKDEAP QLYVLYEKGR NQYMESISLV KVSVYGTL. It is sometimes possible for the material contained within the vial of "Sialidase-1 (NEU1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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