Chaperone protein DnaJ (dnaJ) Recombinant Protein | dnaJ recombinant protein
Recombinant Bacillus amyloliquefaciens Chaperone protein DnaJ (dnaJ)
NCBI and Uniprot Product Information
Uniprot Description
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
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Product Notes
The dnaJ dnaj (Catalog #AAA1101885) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-375, Full length. The amino acid sequence is listed below: MSKRDYYEVL GVSKSASKDE IKKAYRKLSK KYHPDINKES GADEKFKEVK EAYEALSDDQ KRAQYDQFGH TDPNQGFGGG FGGGGDFGGF GFDDIFSSIF GGGTRRRDPN APRQGADLQY TMTLSFEDAA FGKETIIEIP REENCETCKG SGAKPGTKPD TCSHCGGSGQ LNVEQNTPFG KVVNRRVCHH CEGTGKIIKN KCSDCGGTGK VKKRKKINVT IPAGVDDGQQ LRVPGQGEPG VNGGPAGDLF VVFHVRAHEF FERDGDDIYC EMPLTFAQAA LGDEVEVPTL HGKVKLKIPA GTQTGTKFRL RGKGVQNVRG YGQGDQHIVV RVVTPTNLTD KQKDIIREFA EVSGNLPDEQ EMSFFDKVKR AFKGE. It is sometimes possible for the material contained within the vial of "Chaperone protein DnaJ (dnaJ), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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