Protein mgrB (mgrB) Recombinant Protein | mgrB recombinant protein
Recombinant Escherichia coli Protein mgrB (mgrB), partial
NCBI and Uniprot Product Information
NCBI Description
Mg(2+) stimulon-PhoPQ regulon. [More information is available at EcoGene: EG14383]. Transcription of mgrB is induced by low magnesium and is controlled by the PhoP/PhoQ two-component system . [More information is available at EcoCyc: G7002].
Uniprot Description
Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP.
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Product Notes
The mgrB mgrb (Catalog #AAA1091171) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-47. The amino acid sequence is listed below: MKKFRWVVLV VVVLACLLLW AQVFNMMCDQ DVQFFSGICA INQFIPW. It is sometimes possible for the material contained within the vial of "Protein mgrB (mgrB), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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