E3 ubiquitin-protein ligase sspH1 (sspH1) Recombinant Protein | sspH1 recombinant protein
Recombinant Salmonella typhimurium E3 ubiquitin-protein ligase sspH1 (sspH1), partial
NCBI and Uniprot Product Information
Uniprot Description
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin-protein ligase that interferes with the host's ubiquitination pathway and targets host proteins for proteasomal degradation. Can ubiquitinate ubiquitin, giving rise to polyubiquitin chains (in vitro). Polyubiquitinates host PKN1, leading to its proteasomal degradation. Down-modulates production of host proinflammatory cytokines by inhibiting NF-kappa-B-dependent gene expression; this depends only partially on its E3 ubiquitin-protein ligase activity.
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Product Notes
The sspH1 ssph1 (Catalog #AAA1084763) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase sspH1 (sspH1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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