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Streptokinase Active Protein | skc active protein

Recombinant Streptokinase

Purity
Greather than 97% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
Synonyms
Streptokinase; Recombinant Streptokinase; Streptokinase Recombinant; SK; skc active protein
Ordering
Host
E Coli
Purity/Purification
Greather than 97% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered concentrated (1mg/ml) solution in PBS, pH 7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Concentration
1mg/ml (varies by lot)
Sequence
IAGPEWLLDR PSVNNSQLVV SVAGTVEGTN QDISLKFFEI DLTSRPAHGG KTEQGLSPKS KLFATDSGAM PHKLEKADLL KAIQEQLIAN VHSNDDYFEV IDFASDATIT DRNGKVYFAD KDGSVTLPIQ PVQEFLLKGH VRVRPYKEKP VQNQAKSVDV EYTVQFTPLN PDDDFRPALK DTKLLKTLAI GDTITSQELL AQAQSILNKN HPGYTIYERD SSIVTHDNDI FRTILPMDQE FTYHVKNREQ AYRINKKSGL NEEINNTDLI SEKYYVLKKG EKPYDPFDRS HLKLFTIKYV DVNTNELLKS EQLLTASERN LDFRDLYDPR DKAKLLYNNL DAFGIMDYTL TGKVEDNHDD TNRIITVYMG KRPEGENASY HLAYDKDRYT EEEREVYSYL RYTGTPIPDN PNDK
Sequence Length
286
Solubility
It is recommended to reconstitute the lyophilzed Streptokinase in sterile 19Momega-cmH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
The specific biological activity measured by the ability of fibrin lysis in agarose plate was found to be 80000U/mg.
Preparation and Storage
Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Streptokinase should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
Related Product Information for skc active protein
Description: Streptokinase Recombinant produced in E Coli is a non-glycosylated polypeptide chain containing 414 amino acids and having a molecular weight of 47kDa.The Streptokinase is purified by proprietary chromatographic techniques.

Introduction: Streptokinase is an extracellular metallo-enzymeproduced by beta-haemolytic streptococcusand is used as an effective and cheap clot-dissolving medicationin some cases of myocardial infarction(heart attack) and pulmonary embolism.It belongs to a group of medications known as fibrinolytics, and works by activating plasminogenthrough cleavage to produce plasmin.
Product Categories/Family for skc active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
Streptokinase
UniProt Protein Name
Plasminogen activator A
UniProt Gene Name
skc
UniProt Entry Name
Q7B2W0_STRUB

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Product Notes

The Streptokinase skc (Catalog #AAA10820) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: IAGPEWLLDR PSVNNSQLVV SVAGTVEGTN QDISLKFFEI DLTSRPAHGG KTEQGLSPKS KLFATDSGAM PHKLEKADLL KAIQEQLIAN VHSNDDYFEV IDFASDATIT DRNGKVYFAD KDGSVTLPIQ PVQEFLLKGH VRVRPYKEKP VQNQAKSVDV EYTVQFTPLN PDDDFRPALK DTKLLKTLAI GDTITSQELL AQAQSILNKN HPGYTIYERD SSIVTHDNDI FRTILPMDQE FTYHVKNREQ AYRINKKSGL NEEINNTDLI SEKYYVLKKG EKPYDPFDRS HLKLFTIKYV DVNTNELLKS EQLLTASERN LDFRDLYDPR DKAKLLYNNL DAFGIMDYTL TGKVEDNHDD TNRIITVYMG KRPEGENASY HLAYDKDRYT EEEREVYSYL RYTGTPIPDN PNDK. It is sometimes possible for the material contained within the vial of "Streptokinase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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