Coupling protein TraD (traD) Recombinant Protein | traD recombinant protein
Recombinant Escherichia coli Coupling protein TraD (traD)
NCBI and Uniprot Product Information
Uniprot Description
Function: Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell. It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations. Couples the transferosome to a type IV secretion system. Probably forms a pore through which single-stranded plasmid DNA is transferred to the secretion system. The last 37 residues are important for determining plasmid specificity and transfer efficiency, with additional specificity conferred by the TraD-TraM pair. Ref.12
Subunit structure: Interacts with relaxosome component TraM. May form a hexamer in the membrane. Ref.11 Ref.14
Subcellular location: Cell inner membrane; Multi-pass membrane protein Ref.11.
Sequence similarities: Belongs to the TrwB coupling protein family.
Sequence caution: The sequence AAC44181.2 differs from that shown. Reason: Erroneous termination at position 718. Translated as stop.The sequence CAA30013.1 differs from that shown. Reason: Frameshift at position 19.
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Product Notes
The traD trad (Catalog #AAA1080500) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-717. The amino acid sequence is listed below: MSFNAKDMTQ GGQIASMRIR MFSQIANIML YCLFIFFWIL VGLVLWIKIS WQTFVNGCIY WWCTTLEGMR DLIKSQPVYE IQYYGKTFRM NAAQVLHDKY MIWCSEQLWS AFVLAAVVAL VICLITFFVV SWILGRQGKQ QSENEVTGGR QLTDNPKDVA RMLKKDGKDS DIRIGDLPII RDSEIQNFCL HGTVGAGKSE VIRRLANYAR QRGDMVVIYD RSGEFVKSYY DPSIDKILNP LDARCAAWDL WKECLTQPDF DNTANTLIPM GTKEDPFWQG SGRTIFAEAA YLMRNDPNRS YSKLVDTLLS IKIEKLRTYL RNSPAANLVE EKIEKTAISI RAVLTNYVKA IRYLQGIEHN GEPFTIRDWM RGVREDQKNG WLFISSNADT HASLKPVISM WLSIAIRGLL AMGENRNRRV WFFCDELPTL HKLPDLVEIL PEARKFGGCY VFGIQSYAQL EDIYGEKAAA SLFDVMNTRA FFRSPSHKIA EFAAGEIGEK EHLKASEQYS YGADPVRDGV STGKDMERQT LVSYSDIQSL PDLTCYVTLP GPYPAVKLSL KYQTRPKVAP EFIPRDINPE MENRLSAVLA AREAEGRQMA SLFEPDVPEV VSGEDVTQAE QPQQPVSPAI NDKKSDSGVN VPAGGIEQEL KMKPEEEMEQ QLPPGISESG EVVDMAAYEA WQQENHPDIQ QQMQRREEVN INVHRERGED VEPGDDF. It is sometimes possible for the material contained within the vial of "Coupling protein TraD (traD), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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