Hamster Retinoid X Receptor Gamma ELISA Kit | RXRgamma elisa kit
Hamster Retinoid X Receptor Gamma ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Uniprot Description
RXRG: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Belongs to the nuclear hormone receptor family. NR2 subfamily.
Protein type: Nuclear receptor; DNA-binding
Chromosomal Location of Human Ortholog: 1q22-q23
Cellular Component: nucleoplasm
Molecular Function: protein binding; retinoid-X receptor activity; zinc ion binding; steroid hormone receptor activity
Biological Process: neuron differentiation; retinoic acid receptor signaling pathway; transcription initiation from RNA polymerase II promoter; skeletal muscle development; response to retinoic acid; regulation of myelination; heart development; gene expression; steroid hormone mediated signaling; transmembrane transport; protein homotetramerization; peripheral nervous system development
Research Articles on RXRgamma
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Product Notes
The Hamster RXRgamma rxrg (Catalog #AAA107482) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA107482 ELISA Kit recognizes Hamster RXRgamma. It is sometimes possible for the material contained within the vial of "Retinoid X Receptor Gamma, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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