Antigen 85-C (fbpC) Recombinant Protein | fbpC recombinant protein

Recombinant Mycobacterium bovis Antigen 85-C (fbpC)

Cat. Num. AAA1061371

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Antigen 85-C (fbpC); Recombinant Mycobacterium bovis Antigen 85-C (fbpC); fbpC recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 46-340, Full length protein
• Sequence: AFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAFEEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVSPTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGYNANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGLTLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAAPAAPAA
• Sequence Length: 295

• Species: Mycobacterium bovis
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 31791308
• NCBI GeneID: 1090815
• NCBI Accession #: NP_853801.1
• NCBI GenBank Nucleotide #: NC_002945.3
• UniProt Accession #: P0A4V5; P31953; P96806; A0A1R3XUE5; X2BE42
• Molecular Weight: 36,771 Da
• NCBI Official Full Name: secreted antigen 85-C FbpC
• NCBI Official Symbol: fbpC
• NCBI Protein Information: SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C)
• UniProt Protein Name: Diacylglycerol acyltransferase/mycolyltransferase Ag85C
• Protein Family: Fe(3+) ions import ATP-binding protein
• UniProt Gene Name: fbpC
• UniProt Synonym Gene Names: mpt45; DGAT; 85C; Ag85C; Fbps C

Uniprot Description

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM ().