Kinetochore protein Spc25 (Spc25) Recombinant Protein | Spc25 recombinant protein
Recombinant Drosophila mojavensis Kinetochore protein Spc25 (Spc25)
Gene Names
DmojGI23349; dmoj_GLEANR_8490; GI23349
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Kinetochore protein Spc25 (Spc25); Recombinant Drosophila mojavensis Kinetochore protein Spc25 (Spc25); Spc25 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-208, Full length protein
Sequence
MRKRLMAMLQNDISLQQQENALAKQSAKFHSKIAAKHQLIKRQQRKLEKLNQVANERKEDQENRSAFEQSMRDKLLREQQNLSEMQTELATKKQRRDELMGFVRTMSEATNTYINLKALPARVKGVALRPEQGEWIPFNCDAYDLKGLNALWSRLNEPSASTDKWQQLFSAEPTAKEKENANASLSSIIEIDLTSPTAHRSLAKMLEK
Sequence Length
208
Species
Drosophila mojavensis (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,968 Da
NCBI Official Full Name
uncharacterized protein Dmoj_GI23349, isoform A
NCBI Official Symbol
DmojGI23349
NCBI Official Synonym Symbols
dmoj_GLEANR_8490; GI23349
NCBI Protein Information
GI23349 gene product from transcript GI23349-RB
UniProt Protein Name
Kinetochore protein Spc25
Protein Family
UniProt Gene Name
Spc25
Uniprot Description
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
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Product Notes
The Spc25 spc25 (Catalog #AAA1057453) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-208, Full length protein. The amino acid sequence is listed below: MRKRLMAMLQ NDISLQQQEN ALAKQSAKFH SKIAAKHQLI KRQQRKLEKL NQVANERKED QENRSAFEQS MRDKLLREQQ NLSEMQTELA TKKQRRDELM GFVRTMSEAT NTYINLKALP ARVKGVALRP EQGEWIPFNC DAYDLKGLNA LWSRLNEPSA STDKWQQLFS AEPTAKEKEN ANASLSSIIE IDLTSPTAHR SLAKMLEK. It is sometimes possible for the material contained within the vial of "Kinetochore protein Spc25 (Spc25), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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