Mitochondrial import inner membrane translocase subunit TIM54 (TIM54) Recombinant Protein | TIM54 recombinant protein
Recombinant Saccharomyces cerevisiae Mitochondrial import inner membrane translocase subunit TIM54 (TIM54)
NCBI and Uniprot Product Information
Uniprot Description
Function: Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its precise function within the TIM22 complex is unclear. Ref.3 Ref.5 Ref.7
Subunit structure: Component of the TIM22 complex, whose core is composed of TIM18, TIM22 and TIM54, associated with the peripheral proteins MRS5/TIM12 and the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13). Ref.5 Ref.6 Ref.9
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein. Note: Import into inner membrane protein requires TOM70 function. Ref.3 Ref.4 Ref.5 Ref.8
Sequence similarities: Belongs to the TIM54 family.
Research Articles on TIM54
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Product Notes
The TIM54 tim54 (Catalog #AAA1057041) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-478. The amino acid sequence is listed below: MSSESGKPIA KPIRKPGYTN PALKALGIPA LRLPSRNWMI FWSVLTVSIG GIAYDKYKQR QILSHATDLV KPLAEESMEV DKVPRKITVF IAPPPNDYLE SSLKVWRRYV KPVLYYAGLD YELVQEDRQG IIRTNVANRI RELRKEILAS TDGQPVKEPN QTVAKPSGSS TSKISSLLPF NKIIQDPAEE DDSFDPEIGK KFKENFDWRN VIGIFYTMPK PKHIISEDAL TKDPILSGGV ICLGRGAYKE YIAGIHEGLL GPIEKTEKTG STEPKMTGVV EANQIESKVS ESGATELVDA EKETALEEAK VQDDLKVDEE NSSEDSQKFL KPFISSDQYP DLQIASELQT PNGEFIRNPN TNIPLLINQP LLVIPIPNLI GFTTIPRRIH RFYQKRFYVE DVCSSVVNCV RQTRIRPFDI AKDIDLAKDE EKDWPQNWVK QGKEKNSEWT QELVCDPRIT KHMFVYEKPP KEEPESDI. It is sometimes possible for the material contained within the vial of "Mitochondrial import inner membrane translocase subunit TIM54 (TIM54), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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