High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Pde8a) Recombinant Protein | Pde8a recombinant protein

Recombinant Mouse High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Pde8a) , partial

• Gene Names: Pde8a; Pde8; AI551852
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: High affinity cAMP-specific and IBMX-insensitive 3'; 5'-cyclic phosphodiesterase 8A (Pde8a); Recombinant Mouse High affinity cAMP-specific and IBMX-insensitive 3'; partial; Pde8a recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 823

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 6679249
• NCBI GeneID: 18584
• NCBI Accession #: NP_032829.1
• NCBI GenBank Nucleotide #: NM_008803.2
• UniProt Accession #: O88502; Q059P6
• Molecular Weight: 93,171 Da
• NCBI Official Full Name: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
• NCBI Official Synonym Full Names: phosphodiesterase 8A
• NCBI Official Symbol: Pde8a
• NCBI Official Synonym Symbols: Pde8; AI551852
• NCBI Protein Information: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
• UniProt Protein Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
• Protein Family: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase
• UniProt Gene Name: Pde8a
• UniProt Synonym Gene Names: Pde8; MmPDE8

Uniprot Description

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine.