Testing Data
5-HT (Serotonin) 7 Antibody | anti-5HT7 R antibody
5-HT (Serotonin) 7 Receptor Antibody, Rabbit
Gene Names
HTR7; 5-HT7
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Synonyms
5-HT (Serotonin) 7; 5-HT (Serotonin) 7 Receptor Antibody; Rabbit; anti-5HT7 R antibody
Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified - Liquid
Sequence Length
432
Applicable Applications for anti-5HT7 R antibody
Immunohistochemistry (IHC), Western Blot (WB)
Type Info
Rabbit IgG
Immunogen
synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor
Preparation and Storage
Store at 4-8 degrees
Testing Data
Testing Data
Related Product Information for anti-5HT7 R antibody
The histochemical antibody for 5-HT7 receptor is generated in a rabbit against synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor.
The antibody produces 4+ (maximum) labeling of 5-HT7 receptor at dilutions of 1/100 - 1/300 using biotin-avidin/HRP technique in rat cortex and hippocampus. Optimal dilution will vary depending upon fixation, labeling technique and/or detection system; therefore, a dilution series is recommended. The antibody was characterized by immunohistochemistry. Immunohistochemical staining of rat brain correlates well with Northern blot analysis, in situ hybridization and receptor autoradiography studies. Immunolabeling is completely abolished by preadsorption with synthetic rat 5-HT7 receptor (8-23). BlastP database sequence homology searches indicate that the amino acid sequence is unique to rat 5-HT7A, 5-HT7B and 5-HT7C. There is also significant sequence overlap with the mouse and human forms.
The antibody produces 4+ (maximum) labeling of 5-HT7 receptor at dilutions of 1/100 - 1/300 using biotin-avidin/HRP technique in rat cortex and hippocampus. Optimal dilution will vary depending upon fixation, labeling technique and/or detection system; therefore, a dilution series is recommended. The antibody was characterized by immunohistochemistry. Immunohistochemical staining of rat brain correlates well with Northern blot analysis, in situ hybridization and receptor autoradiography studies. Immunolabeling is completely abolished by preadsorption with synthetic rat 5-HT7 receptor (8-23). BlastP database sequence homology searches indicate that the amino acid sequence is unique to rat 5-HT7A, 5-HT7B and 5-HT7C. There is also significant sequence overlap with the mouse and human forms.
Product Categories/Family for anti-5HT7 R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,984 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 7 isoform b
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 7
NCBI Official Symbol
HTR7
NCBI Official Synonym Symbols
5-HT7
NCBI Protein Information
5-hydroxytryptamine receptor 7
UniProt Protein Name
5-hydroxytryptamine receptor 7
UniProt Gene Name
HTR7
UniProt Synonym Gene Names
5-HT-7; 5-HT7
UniProt Entry Name
5HT7R_HUMAN
Uniprot Description
5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 10q21-q24
Cellular Component: dendrite; integral to plasma membrane; plasma membrane
Molecular Function: neurotransmitter receptor activity
Biological Process: blood circulation; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor, adenylate cyclase activating pathway
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Product Notes
The 5HT7 R htr7 (Catalog #AAA555179) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The 5-HT (Serotonin) 7 Receptor Antibody, Rabbit reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's 5-HT (Serotonin) 7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the 5HT7 R htr7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "5-HT (Serotonin) 7, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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