Non-structural protein 2 (1B) Recombinant Protein | NS2 recombinant protein
Recombinant Human respiratory syncytial virus B Non-structural protein 2 (1B)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Non-structural protein 2 (1B); Recombinant Human respiratory syncytial virus B Non-structural protein 2 (1B); NS2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-124, Full length protein
Sequence
MSTTNDNTTMQRLMITDMRPLSMDSIITSLTKEIITHKFIYLINNECIVRKLDERQATFTFLVNYEMKLLHKVGSTKYKKYTEYNTKYGTFPMPIFINHGGFLECIGIKPTKHTPIIYKYDLNP
Sequence Length
124
Species
Human respiratory syncytial virus B (strain B1)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,567 Da
NCBI Official Full Name
non-structural protein 2
NCBI Official Symbol
NS2
NCBI Protein Information
NS2
UniProt Protein Name
Non-structural protein 2
Protein Family
UniProt Gene Name
1B
UniProt Synonym Gene Names
NS2; NS2
Uniprot Description
Plays a major role in antagonizing the type I IFN-mediated antiviral response. Acts cooperatively with NS1 to repress activation and nuclear translocation of host IFN-regulatory factor IRF-3. Interacts with the host cytoplasmic sensor of viral nucleic acids DDX58/RIG-I and prevents the interaction with its downstream partner MAVS. Mediates the proteasomal degradation of host STAT2 with Elongin-Cullin E3 ligase. Induces activation of NF-kappa-B. Suppresses premature apoptosis by an NF-kappa-B-dependent, interferon-independent mechanism and thus facilitates virus growth. May also inhibit viral transcription and RNA replication ().
Research Articles on NS2
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Product Notes
The NS2 1b (Catalog #AAA1118637) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-124, Full length protein. The amino acid sequence is listed below: MSTTNDNTTM QRLMITDMRP LSMDSIITSL TKEIITHKFI YLINNECIVR KLDERQATFT FLVNYEMKLL HKVGSTKYKK YTEYNTKYGT FPMPIFINHG GFLECIGIKP TKHTPIIYKY DLNP. It is sometimes possible for the material contained within the vial of "Non-structural protein 2 (1B), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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