Vacuolar Protein Sorting 29 Recombinant Protein | VPS29 recombinant protein
Recombinant Human Vacuolar Protein Sorting 29
Sterile Filtered colorless solution.
Introduction: VPS29 is a member of a group of genes coding for vacuolar protein sorting (VPS) proteins which, when functionally damaged, lessens the efficient transfer of vacuolar hydrolases. VPS29 is a late Golgi transmembrane protein that operates as the sorting receptor for soluble vacuolar hydrolases, from the prevacuolar endosome back to the Golgi. Moreover, VPS29 takes part in the creation of the inner shell of the retromer coat for retrograde vesicles parting the prevacuolar compartment.
NCBI and Uniprot Product Information
Uniprot Description
VPS29: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Belongs to the VPS29 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein phosphatase, Ser/Thr (non-receptor); Vesicle; EC 3.1.3.3
Cellular Component: membrane; intracellular membrane-bound organelle; cell; retromer complex; cytoplasm; intracellular; endosome
Molecular Function: zinc ion binding; metal ion binding; protein transporter activity
Biological Process: intracellular protein transport; protein transport; transport; Golgi to vacuole transport; retrograde transport, endosome to Golgi
Research Articles on VPS29
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Product Notes
The VPS29 vps29 (Catalog #AAA145255) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMM LVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP. It is sometimes possible for the material contained within the vial of "Vacuolar Protein Sorting 29, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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