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Vacuolar Protein Sorting 29 Recombinant Protein | VPS29 recombinant protein

Recombinant Human Vacuolar Protein Sorting 29

Gene Names
Vps29; PEP11; AW049835; 2010015D08Rik
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Vacuolar Protein Sorting 29; Recombinant Human Vacuolar Protein Sorting 29; VPS29 Human; Vacuolar Protein Sorting 29 Human Recombinant; Vacuolar protein sorting 29 yeast homolog (S. cerevisiae); DC15; PEP11; DC7; retromer protein; x 007 protein; EC 3.1.3.3; VPS29 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The VPS29 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 40% glycerol.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMMLVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP
Sequence Length
182
Related Product Information for VPS29 recombinant protein
Description: VPS29 Human Recombinant produced in E Coli is a single polypeptide chain containing 207 amino acids (1-182) and having a molecular mass of 23.2kDa.VPS29 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: VPS29 is a member of a group of genes coding for vacuolar protein sorting (VPS) proteins which, when functionally damaged, lessens the efficient transfer of vacuolar hydrolases. VPS29 is a late Golgi transmembrane protein that operates as the sorting receptor for soluble vacuolar hydrolases, from the prevacuolar endosome back to the Golgi. Moreover, VPS29 takes part in the creation of the inner shell of the retromer coat for retrograde vesicles parting the prevacuolar compartment.
Product Categories/Family for VPS29 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,917 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 29
NCBI Official Synonym Full Names
vacuolar protein sorting 29 (S. pombe)
NCBI Official Symbol
Vps29
NCBI Official Synonym Symbols
PEP11; AW049835; 2010015D08Rik
NCBI Protein Information
vacuolar protein sorting-associated protein 29; vacuolar sorting protein 29; vesicle protein sorting 29
UniProt Protein Name
Vacuolar protein sorting-associated protein 29
UniProt Gene Name
Vps29
UniProt Entry Name
VPS29_MOUSE

Uniprot Description

VPS29: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Belongs to the VPS29 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); Vesicle; EC 3.1.3.3

Cellular Component: membrane; intracellular membrane-bound organelle; cell; retromer complex; cytoplasm; intracellular; endosome

Molecular Function: zinc ion binding; metal ion binding; protein transporter activity

Biological Process: intracellular protein transport; protein transport; transport; Golgi to vacuole transport; retrograde transport, endosome to Golgi

Research Articles on VPS29

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Product Notes

The VPS29 vps29 (Catalog #AAA145255) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMM LVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP. It is sometimes possible for the material contained within the vial of "Vacuolar Protein Sorting 29, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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