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Immunoglobulin iota chain (VPREB1) Recombinant Protein | VPREB1 recombinant protein

Recombinant Human Immunoglobulin iota chain (VPREB1)

Gene Names
VPREB1; IGI; IGVPB; VPREB; CD179a
Reactivity
Human
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Immunoglobulin iota chain (VPREB1); Recombinant Human Immunoglobulin iota chain (VPREB1); CD179 antigen-like family member A; VPREB1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Human
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Sequence Positions
Full Length, 20-145aa
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Related Product Information for VPREB1 recombinant protein
Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29.86 kDa
NCBI Official Full Name
immunoglobulin iota chain isoform 1
NCBI Official Synonym Full Names
V-set pre-B cell surrogate light chain 1
NCBI Official Symbol
VPREB1
NCBI Official Synonym Symbols
IGI; IGVPB; VPREB; CD179a
NCBI Protein Information
immunoglobulin iota chain
UniProt Protein Name
Immunoglobulin iota chain
Protein Family
UniProt Gene Name
VPREB1
UniProt Synonym Gene Names
VPREB; VpreB protein

NCBI Description

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Uniprot Description

VPREB1: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation. Belongs to the immunoglobulin superfamily.

Chromosomal Location of Human Ortholog: 22q11.22

Cellular Component: extracellular region; extracellular space

Biological Process: immune response; immunoglobulin production; leukocyte migration

Research Articles on VPREB1

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Product Notes

The VPREB1 vpreb1 (Catalog #AAA9423626) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 20-145aa. The Recombinant Human Immunoglobulin iota chain (VPREB1) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Immunoglobulin iota chain (VPREB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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