MRPS33 blocking peptide

MRPS33 Blocking Peptide

Cat. Num. AAA8220267

• Gene Names: MRPS33; S33mt; PTD003; CGI-139; MRP-S33
• Reactivity: Human, Mouse
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: MRPS33; MRPS33 Blocking Peptide; 28S ribosomal protein S33; mitochondrial; MRP-S33; S33mt; MRPS33 blocking peptide

• Host: Synthetic
• Reactivity: Human, Mouse
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 106

• Applicable Applications for MRPS33 blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for MRPS33 blocking peptide

The peptide is used to block Anti-MRPS33 Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 7706349
• NCBI GeneID: 51650
• NCBI Accession #: NP_057155.1
• NCBI GenBank Nucleotide #: NM_016071.3
• UniProt Accession #: Q9Y291
• Molecular Weight: 12,629 Da
• NCBI Official Full Name: 28S ribosomal protein S33, mitochondrial
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein S33
• NCBI Official Symbol: MRPS33
• NCBI Official Synonym Symbols: S33mt; PTD003; CGI-139; MRP-S33
• NCBI Protein Information: 28S ribosomal protein S33, mitochondrial
• UniProt Protein Name: 28S ribosomal protein S33, mitochondrial
• Protein Family: 28S ribosomal protein
• UniProt Gene Name: MRPS33
• UniProt Synonym Gene Names: MRP-S33; S33mt
• UniProt Entry Name: RT33_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008]

Uniprot Description

MRPS33: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein type: Ribosomal; Mitochondrial

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: mitochondrial small ribosomal subunit; mitochondrial inner membrane

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; translation; organelle organization and biogenesis