Adenylate Cyclase 4 Blocking Peptide | ADCY4 blocking peptide

Adenylate Cyclase 4 Blocking Peptide

Cat. Num. AAA8239657

• Gene Names: ADCY4; AC4
• Reactivity: Human, Mouse, Rat
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: Adenylate Cyclase 4; Adenylate Cyclase 4 Blocking Peptide; Adenylate cyclase type 4; ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4; ADCY4 blocking peptide

• Host: Synthetic
• Reactivity: Human, Mouse, Rat
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 1077

• Applicable Applications for ADCY4 blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for ADCY4 blocking peptide

The peptide is used to block Anti-Adenylate Cyclase 4 Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 310832386
• NCBI GeneID: 196883
• NCBI Accession #: NP_001185497.1
• NCBI GenBank Nucleotide #: NM_001198568.1
• UniProt Accession #: Q8NFM4; Q17R40; Q6ZTM6; Q96ML7; B3KV74; D3DS75
• Molecular Weight: 46,245 Da
• NCBI Official Full Name: adenylate cyclase type 4
• NCBI Official Synonym Full Names: adenylate cyclase 4
• NCBI Official Symbol: ADCY4
• NCBI Official Synonym Symbols: AC4
• NCBI Protein Information: adenylate cyclase type 4
• UniProt Protein Name: Adenylate cyclase type 4
• Protein Family: Adenylate cyclase
• UniProt Gene Name: ADCY4
• UniProt Entry Name: ADCY4_HUMAN

NCBI Description

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]

Uniprot Description

ADCY4: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Membrane protein, integral; EC 4.6.1.1; Lyase; Transporter; Transporter, aquaporin family; Nucleotide Metabolism - purine; Membrane protein, multi-pass; Adenylyl cyclase

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: membrane; cytoplasm; dendrite; integral to membrane; plasma membrane

Molecular Function: protein binding; metal ion binding; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; synaptic transmission; phospholipase C activation; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport