Mouse suppressor of cytokine signaling 7 ELISA Kit | SOCS7 elisa kit
Mouse Suppressor of cytokine signaling 7, SOCS7 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SOCS7: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF- like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Inhibitor
Cellular Component: membrane; intracellular membrane-bound organelle; cytoplasm; nucleolus; plasma membrane; nucleus
Molecular Function: protein binding; protein kinase inhibitor activity
Biological Process: fat cell differentiation; radial glia guided migration of Purkinje cell; cytokine and chemokine mediated signaling pathway; regulation of growth; insulin receptor signaling pathway; protein ubiquitination; negative regulation of protein kinase activity; cerebral cortex radially oriented cell migration; negative regulation of JAK-STAT cascade; layer formation in the cerebral cortex; negative regulation of signal transduction
Research Articles on SOCS7
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Product Notes
The Mouse SOCS7 socs7 (Catalog #AAA9320196) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320196 ELISA Kit recognizes Mouse SOCS7. It is sometimes possible for the material contained within the vial of "suppressor of cytokine signaling 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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