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Suppressor of IKBKE 1 (Sike1) Recombinant Protein | Sike1 recombinant protein

Recombinant Mouse Suppressor of IKBKE 1 (Sike1)

Gene Names
Sike1; Sike; Sikeb; AI450236; AI839862; 2810005O12Rik; 5730470L24Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Suppressor of IKBKE 1 (Sike1); Recombinant Mouse Suppressor of IKBKE 1 (Sike1); Sike1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-207, full length protein
Sequence
MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGAVLPEQYQEDASDVKDMSKYKPHILLSQENTQIRDLQQENRELWVSLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGAVMRRAVQVDDNQFCKVQERLAQLELENKELRELLSISSESLQVGKESSVAPASQTIK
Sequence Length
207
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,522 Da
NCBI Official Full Name
suppressor of IKBKE 1
NCBI Official Synonym Full Names
suppressor of IKBKE 1
NCBI Official Symbol
Sike1
NCBI Official Synonym Symbols
Sike; Sikeb; AI450236; AI839862; 2810005O12Rik; 5730470L24Rik
NCBI Protein Information
suppressor of IKBKE 1
UniProt Protein Name
Suppressor of IKBKE 1
Protein Family
UniProt Gene Name
Sike1

Uniprot Description

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways ().

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Product Notes

The Sike1 sike1 (Catalog #AAA1369844) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-207, full length protein. The amino acid sequence is listed below: MSCTIEKILT DAKTLLERLR EHDAAAESLV DQSAALHRRV AAMREAGAVL PEQYQEDASD VKDMSKYKPH ILLSQENTQI RDLQQENREL WVSLEEHQDA LELIMSKYRK QMLQLMVAKK AVDAEPVLKA HQSHSAEIES QIDRICEMGA VMRRAVQVDD NQFCKVQERL AQLELENKEL RELLSISSES LQVGKESSVA PASQTIK. It is sometimes possible for the material contained within the vial of "Suppressor of IKBKE 1 (Sike1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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