Raftlin (Rftn1) Recombinant Protein | Rftn1 recombinant protein
Recombinant Mouse Raftlin (Rftn1)
Gene Names
Rftn1; AI853526; 2310015N21Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Raftlin (Rftn1); Recombinant Mouse Raftlin (Rftn1); Rftn1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-554, Full length protein
Sequence
GCSLNKLEKREEKRPGNIYSTLKRPQVETKVDVTYEYCFLEFTTLTAAELPRSSATRLASLRDLPDQLLELYQQGFSLAALHPFVQPTRRQEKILLEHIFRAILVKKTNRSQKAELHDEGYTLELDYCSSLEHLADQKLIPEFIKKVQEAASQGLKFVSVVPQYQPSVSSAGSRRLKPVANSVEDARDVKCTLGDRSSLENDTPKAAETDAATAGVNRRPETKPGSTGDVPSAQQPGIPSPSAENEAGEFPLRGLQPALDRSEGDPSNGPEELPSRKMEIFAFFNRPKSQQKCRQYYPVTIPLQVSKNGQTVSSLDASWLEHMSDHFRKGGVLVNAVFQLGMANDSFYGLTDGVFIFEAVSTEDNRTTQGYDAIVVEQWTVLEGTEVQTDYMPLLNSLAAYGWQLTCVLPTPILKTTREGNVSTKQIVFLQRPCLPQKTKKRESKFQWRFSRNEIHGRQTRKSKGKLSASNKQQAEENEKNLEDQFSKAGDVGNCVLGAPQWGRASEVREQRQGSAAVQNGPAGHNRDSVALRHSNPRAEAELAAGPTPTEAN
Sequence Length
553
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,537 Da
NCBI Official Full Name
raftlin
NCBI Official Synonym Full Names
raftlin lipid raft linker 1
NCBI Official Symbol
Rftn1
NCBI Official Synonym Symbols
AI853526; 2310015N21Rik
NCBI Protein Information
raftlin
UniProt Protein Name
Raftlin
Protein Family
UniProt Gene Name
Rftn1
UniProt Synonym Gene Names
Kiaa0084
Uniprot Description
Involved in protein trafficking via association with clathrin and AP2 complex (). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (PubMed:19414744). May regulate B-cell antigen receptor-mediated signaling (). May play a pivotal role in the formation and/or maintenance of lipid rafts ().
Research Articles on Rftn1
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Product Notes
The Rftn1 rftn1 (Catalog #AAA1420523) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-554, Full length protein. The amino acid sequence is listed below: GCSLNKLEKR EEKRPGNIYS TLKRPQVETK VDVTYEYCFL EFTTLTAAEL PRSSATRLAS LRDLPDQLLE LYQQGFSLAA LHPFVQPTRR QEKILLEHIF RAILVKKTNR SQKAELHDEG YTLELDYCSS LEHLADQKLI PEFIKKVQEA ASQGLKFVSV VPQYQPSVSS AGSRRLKPVA NSVEDARDVK CTLGDRSSLE NDTPKAAETD AATAGVNRRP ETKPGSTGDV PSAQQPGIPS PSAENEAGEF PLRGLQPALD RSEGDPSNGP EELPSRKMEI FAFFNRPKSQ QKCRQYYPVT IPLQVSKNGQ TVSSLDASWL EHMSDHFRKG GVLVNAVFQL GMANDSFYGL TDGVFIFEAV STEDNRTTQG YDAIVVEQWT VLEGTEVQTD YMPLLNSLAA YGWQLTCVLP TPILKTTREG NVSTKQIVFL QRPCLPQKTK KRESKFQWRF SRNEIHGRQT RKSKGKLSAS NKQQAEENEK NLEDQFSKAG DVGNCVLGAP QWGRASEVRE QRQGSAAVQN GPAGHNRDSV ALRHSNPRAE AELAAGPTPT EAN. It is sometimes possible for the material contained within the vial of "Raftlin (Rftn1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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