Rat Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB) ELISA Kit | PIK3CB elisa kit
Rat Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may play a role in hepatocyte proliferation and DNA replication [RGD, Feb 2006]
Uniprot Description
PIK3CB: catalytic subunit of phosphoinositide-3-kinase beta. Catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration and cell survival. PTEN reverses this process, and the PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN. Expressed ubiquitously.
Protein type: Kinase, lipid; EC 2.7.1.153; Carbohydrate Metabolism - inositol phosphate; Motility/polarity/chemotaxis
Cellular Component: cell; brush border membrane; nucleus; cytosol; phosphoinositide 3-kinase complex
Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; insulin receptor substrate binding; 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4-phosphate 3-kinase activity; ATP binding; phosphoinositide 3-kinase activity
Biological Process: cellular calcium ion homeostasis; platelet activation; phosphoinositide-mediated signaling; phosphoinositide phosphorylation; regulation of cell-matrix adhesion; autophagy; endocytosis; homophilic cell adhesion; cell adhesion; embryonic cleavage
Research Articles on PIK3CB
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Product Notes
The Rat PIK3CB pik3cb (Catalog #AAA9337350) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337350 ELISA Kit recognizes Rat PIK3CB. It is sometimes possible for the material contained within the vial of "Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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