Rabbit anti-Human Vasoactive intestinal Polypeptide Receptor 2 Polyclonal Antibody | anti-VIPR2 antibody
Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2
Gene Names
VIPR2; VPAC2; SCZD16; VPCAP2R; FLJ16511
Reactivity
Human
Applications
ELISA
Purity
SerumSerum
Synonyms
Vasoactive intestinal Polypeptide Receptor 2; Polyclonal Antibody; Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2; VIP2R; VIPR2; Helodermin Preferring VIP Receptor; Helodermin-preferring VIP Receptor; Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor; PACAP Type III Receptor; VPAC2; Anti -Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2; anti-VIPR2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human Vasoactive Intestinal Peptide-Receptor 2
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Applicable Applications for anti-VIPR2 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Immunogen
Synthetic human VIP-R2 (aa 3-14) (RFHLEIQEEETK)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-VIPR2 antibody
Vasoactive intestinal peptide (VIP) is a 28-aminoacid peptide (human, chr 6q26-q27). Expressed and secreted by neurons innervating primary and secondary immune organs such as lymph nodes with a Mol.wt of 20kD. VIP is a potent neurotrophic factor causes vasodilation, lowers arterial blood pressure, and relaxes the smooth muscle of trachea, stomach and gall bladder. VIP also modulates several T-lymphocyte activities including motility, cytokine production, proliferation and apoptosis, VIP exerts its biological activity by binding to two closely related class II G-protein-coupled receptors VPAC-1 and VPAC-2 beside this VIP has its own receptors VIPR1&2 (Vasoactive Intestinal Polypeptide Receptor 1&2) and VIPRRP (VIP receptor-gene repressor protein). VIP shows similarities to glucagon, secretin and gastric inhibitory peptide (GIP) as such it has been considered a member of the glucagon-secretin family. The VIP is 100% conserved in mouse, rat and human. VIP is considered to be a viable candidate for the development of treatments for rheumatoid arthritis, since treatment with VIP significantly reduced incidence of severity of arthritis, the therapeutic effect of VIP was associated with downregulation of both inflammatory and autoimmune components of the disease.
Product Categories/Family for anti-VIPR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,479 Da
NCBI Official Full Name
vasoactive intestinal polypeptide receptor 2
NCBI Official Synonym Full Names
vasoactive intestinal peptide receptor 2
NCBI Official Symbol
VIPR2
NCBI Official Synonym Symbols
VPAC2; SCZD16; VPCAP2R; FLJ16511
NCBI Protein Information
vasoactive intestinal polypeptide receptor 2; VIP-R-2; PACAP-R3; PACAP-R-3; OTTHUMP00000200015; OTTHUMP00000200016; OTTHUMP00000200017; PACAP type III receptor; helodermin-preferring VIP receptor; pituitary adenylate cyclase-activating polypeptide type III receptor
UniProt Protein Name
Vasoactive intestinal polypeptide receptor 2
Protein Family
UniProt Gene Name
VIPR2
UniProt Synonym Gene Names
VIP2R
UniProt Entry Name
VIPR2_HUMAN
NCBI Description
Vasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM 102981).[supplied by OMIM]
Uniprot Description
VIPR2: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. Belongs to the G-protein coupled receptor 2 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 2
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; vasoactive intestinal polypeptide receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; negative regulation of smooth muscle cell proliferation; adenylate cyclase activation; signal transduction
Research Articles on VIPR2
Similar Products
Product Notes
The VIPR2 vipr2 (Catalog #AAA621410) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Vasoactive intestinal Polypeptide Receptor 2 (VIP Receptor 2, VIP2R, VIPR2, Helodermin Preferring VIP Receptor, Helodermin-preferring VIP Receptor, Pituitary Adenylate Cyclase Activating Polypeptide Type III Receptor, PACAP Type III Receptor, VPAC2, VPAC2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Vasoactive intestinal Polypeptide Receptor 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the VIPR2 vipr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vasoactive intestinal Polypeptide Receptor 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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