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Rabbit anti-Human, Mouse TSPAN6 Polyclonal Antibody | anti-TSPAN6 antibody

TSPAN6 Antibody, Biotin conjugated

Gene Names
TSPAN6; T245; TM4SF6; TSPAN-6
Reactivity
Human, Mouse
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
TSPAN6; Polyclonal Antibody; TSPAN6 Antibody; Biotin conjugated; Tetraspanin-6; Tspan-6; TM4SF6; UNQ767/PRO1560; A15 homolog; Putative NF-kappa-B-activating protein 321; T245 protein; Tetraspanin TM4-D; Transmembrane 4 superfamily member 6; anti-TSPAN6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
129
Applicable Applications for anti-TSPAN6 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Biotin
Immunogen
Recombinant human Tetraspanin-6 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-244512 / sc-244513 / sc-244514
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-TSPAN6 antibody
extracellular exosome, integral component of plasma membrane, signal transducer activity, cell surface receptor signaling pathway, negative regulation of NIK/NF-kappaB signaling, negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB signaling

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,563 Da
NCBI Official Full Name
tetraspanin-6 isoform d
NCBI Official Synonym Full Names
tetraspanin 6
NCBI Official Symbol
TSPAN6
NCBI Official Synonym Symbols
T245; TM4SF6; TSPAN-6
NCBI Protein Information
tetraspanin-6
UniProt Protein Name
Tetraspanin-6
UniProt Gene Name
TSPAN6
UniProt Synonym Gene Names
TM4SF6; Tspan-6
UniProt Entry Name
TSN6_HUMAN

NCBI Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]

Uniprot Description

TSPAN6: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: integral to plasma membrane

Molecular Function: protein binding; signal transducer activity

Biological Process: cell surface receptor linked signal transduction; positive regulation of I-kappaB kinase/NF-kappaB cascade

Research Articles on TSPAN6

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Product Notes

The TSPAN6 tspan6 (Catalog #AAA1494721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSPAN6 Antibody, Biotin conjugated reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSPAN6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the TSPAN6 tspan6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSPAN6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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