Rabbit anti-Human TRAT1 Polyclonal Antibody | anti-TRAT1 antibody
TRAT1 Antibody
Gene Names
TRAT1; TRIM; TCRIM; HSPC062
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TRAT1; Polyclonal Antibody; TRAT1 Antibody; HSPC062; pp29/30; T cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; TRAT1_HUMAN; TRIM; anti-TRAT1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TRAT1 Antibody detects endogenous levels of TRAT1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TRAT1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human TRAT1.
Conjugation
Unconjugated
Post Translational Modifications
Phosphorylated on tyrosines by LCK or FYN upon TCR activation.
Subunit Structure
Homodimer; disulfide-linked. Interacts with CD3Z. When phosphorylated, interacts with PIK3R1.
Tissue Specificity
Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
Function
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TRAT1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,211 Da
NCBI Official Full Name
T-cell receptor-associated transmembrane adapter 1
NCBI Official Synonym Full Names
T cell receptor associated transmembrane adaptor 1
NCBI Official Symbol
TRAT1
NCBI Official Synonym Symbols
TRIM; TCRIM; HSPC062
NCBI Protein Information
T-cell receptor-associated transmembrane adapter 1; pp29/30; T cell receptor interacting molecule; T-cell receptor interacting molecule; T-cell receptor-interacting molecule
UniProt Protein Name
T-cell receptor-associated transmembrane adapter 1
Protein Family
UniProt Gene Name
TRAT1
UniProt Synonym Gene Names
TCRIM; TRIM
UniProt Entry Name
TRAT1_HUMAN
Uniprot Description
TRAT1: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Protein type: Membrane protein, integral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 3q13
Cellular Component: T cell receptor complex; integral to plasma membrane; plasma membrane
Molecular Function: transmembrane receptor protein tyrosine kinase adaptor protein activity
Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; positive regulation of T cell receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; cellular defense response; innate immune response; positive regulation of calcium-mediated signaling; negative regulation of receptor recycling; negative regulation of transport; signal transduction; T cell receptor signaling pathway
Research Articles on TRAT1
Similar Products
Product Notes
The TRAT1 trat1 (Catalog #AAA9631073) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRAT1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TRAT1 trat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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