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Rabbit anti-Mouse, Rat Sialoadhesin/CD169 Polyclonal Antibody | anti-CD169 antibody

Sialoadhesin/CD169 Polyclonal Antibody PE Conjugated

Gene Names
Siglec1; Sn; Cd169; Siglec-1
Reactivity
Mouse, Rat
Applications
Immunocytochemistry, Immunofluorescence
Purity
affinity purified by Protein A
Synonyms
Sialoadhesin/CD169; Polyclonal Antibody; Sialoadhesin/CD169 Polyclonal Antibody PE Conjugated; anti-CD169 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-CD169 antibody
Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
ICC: 1:50-200
IF: 1:50-200
Conjugation
PE
Immunogen Type
1301-1400/1709
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Product Categories/Family for anti-CD169 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
172,769 Da
NCBI Official Full Name
Sialoadhesin
NCBI Official Synonym Full Names
sialic acid binding Ig-like lectin 1, sialoadhesin
NCBI Official Symbol
Siglec1
NCBI Official Synonym Symbols
Sn; Cd169; Siglec-1
NCBI Protein Information
sialoadhesin; SER; sheep erythrocyte receptor; sialic acid-binding Ig-like lectin 1
UniProt Protein Name
Sialoadhesin
UniProt Gene Name
Siglec1
UniProt Synonym Gene Names
Sa; Sn; SER; Siglec-1
UniProt Entry Name
SN_MOUSE

Uniprot Description

SIGLEC1: Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hemopoiesis. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; extracellular region; integral to membrane; plasma membrane

Molecular Function: protein binding; carbohydrate binding

Biological Process: endocytosis; cell adhesion

Research Articles on CD169

Similar Products

Product Notes

The CD169 siglec1 (Catalog #AAA9463209) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Sialoadhesin/CD169 Polyclonal Antibody PE Conjugated reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Sialoadhesin/CD169 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF). ICC: 1:50-200 IF: 1:50-200. Researchers should empirically determine the suitability of the CD169 siglec1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sialoadhesin/CD169, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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