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Rabbit Adenylate Cyclase III Polyclonal Antibody | anti-ADCY3 antibody

Anti-Adenylate Cyclase III

Reactivity
Human, mouse, rat
Applications
Immunofluorescence, Western Blot
Purity
Affinity purified rabbit polyclonal antibody.
Synonyms
Adenylate Cyclase III; Polyclonal Antibody; Anti-Adenylate Cyclase III; anti-ADCY3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Specificity
Specific for the ~160 kDa adenylate cyclase III protein.
Purity/Purification
Affinity purified rabbit polyclonal antibody.
Form/Format
100 uL in PBS.
Sequence Length
1144
Applicable Applications for anti-ADCY3 antibody
Immunofluorescence (IF) and Western blots (WB)
Application Notes
IF: 1:500

WB: 2000
Quality Control Tests
Western blots performed on each lot.
Preparation and Storage
Store at -20°C in undiluted aliquots; stable for at least 1 year.

Avoid freeze/thaw cycles.
Related Product Information for anti-ADCY3 antibody
Rabbit polyclonal antibody
References
• Fuchs JL, Schwark HD. (2004) Neuronal primary cilia: a review. Cell Biol Int. 28:111-8.
• Louvi A and Grove EA. (2011) Cilia in the CNS: the quiet organelle claims center stage. Neuron 69:1046-1060

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
adenylate cyclase type 3
NCBI Official Synonym Full Names
adenylate cyclase 3
NCBI Official Symbol
Adcy3
NCBI Protein Information
adenylate cyclase type 3; AC3; AC-III; adenylyl cyclase 3; ATP pyrophosphate-lyase 3; type III adenylyl cyclase; adenylate cyclase type III; adenylate cyclase, olfactive type
UniProt Protein Name
Adenylate cyclase type 3
Protein Family
UniProt Gene Name
Adcy3
UniProt Synonym Gene Names
AC-III; AC3
UniProt Entry Name
ADCY3_RAT

NCBI Description

enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate [RGD, Feb 2006]

Uniprot Description

Function: Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.

Catalytic activity: ATP = 3',5'-cyclic AMP + diphosphate.

Cofactor: Binds 2 magnesium ions per subunit

By similarity.

Enzyme regulation: Activated by calcium/calmodulin.

Subcellular location: Membrane; Multi-pass membrane protein.

Tissue specificity: Cilia of the olfactory epithelium.

Induction: By stimulatory G protein (G(s)), forskolin and ALF4-.

Sequence similarities: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.Contains 2 guanylate cyclase domains.

Research Articles on ADCY3

Similar Products

Product Notes

The ADCY3 adcy3 (Catalog #AAA502204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Adenylate Cyclase III reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylate Cyclase III can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF) and Western blots (WB). IF: 1:500

WB: 2000. Researchers should empirically determine the suitability of the ADCY3 adcy3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase III, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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