Human Phospholipase D3 ELISA Kit | PLD3 elisa kit
Human Phospholipase D3 (PLD3) ELISA Kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate PLD3 in Human serum, plasma. An antibody specific for PLD3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PLD3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PLD3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLD3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot Description
PLD3: Belongs to the phospholipase D family.
Protein type: EC 3.1.4.4; Endoplasmic reticulum; Membrane protein, integral; Phospholipase
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: endoplasmic reticulum membrane; extracellular exosome; integral component of membrane
Molecular Function: N-acylphosphatidylethanolamine-specific phospholipase D activity; phospholipase D activity; protein binding
Biological Process: lipid catabolic process
Disease: Alzheimer Disease 19; Spinocerebellar Ataxia 46
Research Articles on PLD3
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Product Notes
The Human PLD3 pld3 (Catalog #AAA281787) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA281787 ELISA Kit recognizes Human PLD3. It is sometimes possible for the material contained within the vial of "Phospholipase D3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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