Rat mortality factor 4 like 2 ELISA Kit | MORF4L2 elisa kit
Rat Mortality factor 4-like protein 2, MORF4L2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MORF4L2: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones (By similarity)
Cellular Component: nucleoplasm; nucleolus
Biological Process: transcription, DNA-dependent; regulation of growth; positive regulation of transcription from RNA polymerase II promoter; chromatin modification; positive regulation of striated muscle cell differentiation; DNA repair
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Product Notes
The Rat MORF4L2 morf4l2 (Catalog #AAA9336122) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336122 ELISA Kit recognizes Rat MORF4L2. It is sometimes possible for the material contained within the vial of "mortality factor 4 like 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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