Mouse anti-Mouse Prekallikrein Monoclonal Antibody | anti-KLKB1 antibody
Biotin Labeled Inhibitory Anti Mouse Prekallikrein, Clone 13G5
Does not compete with PK3A10, PK5G7, PK7G2, PK11H4, or PK14E3 as determined by competitive ELISA.
NCBI and Uniprot Product Information
Target Molecular Weight: 81,000
NCBI Description
This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic processing to generate a disulfide-linked heterodimeric enzyme comprised of heavy and light chains. A complete deletion of the encoded protein prevents occlusive thrombus formation in mice with a minimal role in provoked bleeding. [provided by RefSeq, May 2016]
Uniprot Description
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Research Articles on KLKB1
Similar Products
Product Notes
The KLKB1 klkb1 (Catalog #AAA136100) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Biotin Labeled Inhibitory Anti Mouse Prekallikrein, Clone 13G5 reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Prekallikrein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibitory Antibody, Western Blot (WB). Researchers should empirically determine the suitability of the KLKB1 klkb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prekallikrein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
