Leucine zipper putative tumor suppressor 1 (Lzts1) Recombinant Protein | Lzts1 recombinant protein
Recombinant Mouse Leucine zipper putative tumor suppressor 1 (Lzts1)
Gene Names
Lzts1; F37; FEZ1; PSD-Zip70
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Leucine zipper putative tumor suppressor 1 (Lzts1); Recombinant Mouse Leucine zipper putative tumor suppressor 1 (Lzts1); Lzts1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-599, Full length protein
Sequence
GSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRGKSSSKMGKSEDFFYIKVSQKARGSHRPDYTALSSGDIGGQTGVDFDPATPPKLMPFSNQLEMSSDKGAVRPTAFKPVLPRSGAILHSSPESTSHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQLDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKADKGASCVRSPLSTDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQTFEERPRRTRDELECLEPKSKLKPPSQKSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQKSGEISLLKQQLKESQLEVNTKASEILSLKAQLKDTRGKLDGMELKTQDLESALRTKGLELEVCENELQRKKNEAELLREKVNLLEQELMELRAQAALHPAPLGPPGVGLTFSEDIPALQRELDRLRAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQRQLQQSYLAMYQRNQRLEKALQQLARGDGPGEPFEIDLEGADIPYEDIIATEI
Sequence Length
598
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Lzts1 recombinant protein
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1
cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
67,290 Da
NCBI Official Full Name
leucine zipper putative tumor suppressor 1
NCBI Official Synonym Full Names
leucine zipper, putative tumor suppressor 1
NCBI Official Symbol
Lzts1
NCBI Official Synonym Symbols
F37; FEZ1; PSD-Zip70
NCBI Protein Information
leucine zipper putative tumor suppressor 1
UniProt Protein Name
Leucine zipper putative tumor suppressor 1
Protein Family
UniProt Gene Name
Lzts1
UniProt Synonym Gene Names
Fez1
Uniprot Description
Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as tumor suppressor ().
Research Articles on Lzts1
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Product Notes
The Lzts1 lzts1 (Catalog #AAA953676) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-599, Full length protein. The amino acid sequence is listed below: GSVSSLISGH SFHSKHCRAS QYKLRKSSHL KKLNRYSDGL LRFGFSQDSG RGKSSSKMGK SEDFFYIKVS QKARGSHRPD YTALSSGDIG GQTGVDFDPA TPPKLMPFSN QLEMSSDKGA VRPTAFKPVL PRSGAILHSS PESTSHQLHP MPPDKPKEQE LKPGLCSGAL SDSGRNSMSS LPTHSTTSSY QLDPLVTPVG PTSRFGGSAH NITQGIILQD SNMMSLKALS FSDGGSKLAH PGKADKGASC VRSPLSTDEC TIQELEQKLL QRETALQKLQ RSFDEKEFAS GQTFEERPRR TRDELECLEP KSKLKPPSQK SQRTQQVLQL QVLQLQQEKR QLRQELESLM KEQDLLETKL RSYEREKTNF APALEETQWE VCQKSGEISL LKQQLKESQL EVNTKASEIL SLKAQLKDTR GKLDGMELKT QDLESALRTK GLELEVCENE LQRKKNEAEL LREKVNLLEQ ELMELRAQAA LHPAPLGPPG VGLTFSEDIP ALQRELDRLR AELKEERQGH DQMSSGFQHE RLVWKEEKEK VIQYQRQLQQ SYLAMYQRNQ RLEKALQQLA RGDGPGEPFE IDLEGADIPY EDIIATEI. It is sometimes possible for the material contained within the vial of "Leucine zipper putative tumor suppressor 1 (Lzts1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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