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Lysophospholipase II Recombinant Protein | LYPLA2 recombinant protein

Recombinant Human Lysophospholipase II

Gene Names
LYPLA2; APT2; APT-2; DJ886K2.4
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Lysophospholipase II; Recombinant Human Lysophospholipase II; LYPLA2 Human; Lysophospholipase II Human Recombinant; Acyl-protein thioesterase 2; APT-2; LPL-II; LysoPLA II; LYPLA2; APT2; DJ886K2.4; LYPLA2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The LYPLA2 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 10% glycerol and 100mM NaCl.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYPGVMH SSCPQEMAAV KEFLEKLLPP V
Sequence Length
231
Related Product Information for LYPLA2 recombinant protein
Description: LYPLA2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 251 amino acids (1-231 a.a.) and having a molecular mass of 26.9kDa. The LYPLA2 is purified by proprietary chromatographic techniques.

Introduction: Acyl-protein thioesterase 2 (LYPLA2) is lysophospholipase which acts on biological membranes to regulate the multifunctional lysophospholipids. LYPLA2 may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS.
Product Categories/Family for LYPLA2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,737 Da
NCBI Official Full Name
acyl-protein thioesterase 2
NCBI Official Synonym Full Names
lysophospholipase II
NCBI Official Symbol
LYPLA2
NCBI Official Synonym Symbols
APT2; APT-2; DJ886K2.4
NCBI Protein Information
acyl-protein thioesterase 2; LPL-II; lysoPLA II
UniProt Protein Name
Acyl-protein thioesterase 2
Protein Family
UniProt Gene Name
LYPLA2
UniProt Synonym Gene Names
APT2; APT-2; LPL-II; LysoPLA II
UniProt Entry Name
LYPA2_HUMAN

NCBI Description

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008]

Uniprot Description

LYPLA2: May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity. Deacylates GAP43. Belongs to the AB hydrolase 2 family.

Protein type: EC 3.1.2.-; Phospholipase; Lipid Metabolism - glycerophospholipid

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: cytoplasm

Molecular Function: hydrolase activity

Biological Process: fatty acid metabolic process

Research Articles on LYPLA2

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Product Notes

The LYPLA2 lypla2 (Catalog #AAA144523) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYPGVMH SSCPQEMAAV KEFLEKLLPP V. It is sometimes possible for the material contained within the vial of "Lysophospholipase II, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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