Mouse LATS, large tumor suppressor, homolog 2 (Drosophila) ELISA Kit | LATS2 elisa kit
Mouse Serine/threonine-protein kinase LATS2, LATS2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
LATS2: an AGC kinase of the NDR family of kinases. A tumor suppressor of the LATS family. Plays a critical role in centrosome duplication, maintenance of mitotic fidelity and genomic stability. Inhibits cell growth at the G1/S transition by down-regulating cyclin E/CDK2 kinase activity. Negative regulator of the androgen receptor. Interacts with and is phosphorylated by STK6. Ectopic expression induces apoptosis in lung cancer cell lines. Negatively regulates androgen receptor, and is downregulated in prostate cancer
Protein type: Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Nuclear receptor co-regulator; Tumor suppressor; AGC group; NDR family
Cellular Component: spindle pole; cytoskeleton; cytoplasm; microtubule organizing center; intracellular; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: keratinocyte differentiation; mitosis; hormone-mediated signaling; cell division; negative regulation of cyclin-dependent protein kinase activity; regulation of organ growth; cell cycle; phosphorylation; protein amino acid phosphorylation; G1/S transition of mitotic cell cycle
Research Articles on LATS2
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Product Notes
The Mouse LATS2 lats2 (Catalog #AAA9333666) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333666 ELISA Kit recognizes Mouse LATS2. It is sometimes possible for the material contained within the vial of "LATS, large tumor suppressor, homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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