Glycosyltransferase-like protein LARGE2 (Gyltl1b) Recombinant Protein | Gyltl1b recombinant protein
Recombinant Rat Glycosyltransferase-like protein LARGE2 (Gyltl1b), partial
NCBI and Uniprot Product Information
Uniprot Description
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.
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Product Notes
The Gyltl1b large2 (Catalog #AAA1297798) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-690. The amino acid sequence is listed below: MLPRGRPRAL GAALLLLLLL VVGFFLFGRD PEYGLGTTAT LDGDPYGSRN RSTSSLQLLL PPKCEMLHVA IVCAGYNSSR EIITLMKSVL FYRKNPLHLH LITDAVARNI LETLFRTWMV PAVVVSFYDA EELKPLVSWI PNKHYSGLYG LMKLVLPSVL PLSLARVIVL DTDVTFSSDI MELWALFGHF SDKQVVGLVE NQSDWYLGNL WKNHRPWPAL GRGFNTGVIL LWLDRLQQIG WEQMWKLTAK RELLTLTATS LADQDIFNAV IKEHPELVHP LPCVWNVQLS DHTLAERCYL EAADLKVIHW NSPKKLRVKN KHAEFFRDLH LTFLGFDGKL LCRELFGCPN QFPPGVEQLQ QALAQLDEEE PCFEFRQQQL TVHRVHITFL SHQPPPPRPH DVTLVAQLSM DRLQMLEALC RHWRGPMSLA LYLTDAEAQQ FLRFVETSPV LSARKDVAYH VVYRDGPLYP VNQLRNVALA QALTPYVFLS DIDFLPAYSL YDYLRASIEQ LALGRRQRKA ALVVPAFETL HYRFSFPNSK AELLTLLDAG SLHTFRYHEW PQGHASTDYT RWREAQAPYR VQWSADYEPY VVVPRDCPRY DPRFVGFGWN KVAHIIELDA QEYEFLVLPE AFSIHLPHAP SLDISRFRSS PTYRDCLQAL KEEFHQDLSR RYGSAALKYL TALQQSRSRA. It is sometimes possible for the material contained within the vial of "Glycosyltransferase-like protein LARGE2 (Gyltl1b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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