Human Putative ataxin-3-like protein (ATXN3L) ELISA Kit | ATXN3L elisa kit
Human Putative ataxin-3-like protein (ATXN3L) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011]
Uniprot Description
ataxin-3L: Deubiquitinating enzyme that cleaves both 'Lys-48'- linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro).
Protein type: Protease; Ubiquitin-specific protease; EC 3.4.19.12
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: mitochondrial matrix; mitochondrial membrane; nuclear inclusion body
Molecular Function: omega peptidase activity; ubiquitin protein ligase binding; ubiquitin-specific protease activity; histone deacetylase activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination; regulation of transcription, DNA-dependent; transcription, DNA-dependent; misfolded or incompletely synthesized protein catabolic process
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Product Notes
The Human ATXN3L atxn3l (Catalog #AAA9334165) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334165 ELISA Kit recognizes Human ATXN3L. It is sometimes possible for the material contained within the vial of "Putative ataxin-3-like protein (ATXN3L), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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