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ELAV2/4 Blocking Peptide | ELAVL2 blocking peptide

ELAV2/4 Blocking Peptide

Gene Names
ELAVL2; HUB; HELN1; HEL-N1
Applications
Blocking/Control
Purity
The purity is >90%,tested by HPLC and MS.
Synonyms
ELAV2/4; ELAV2/4 Blocking Peptide; ELAV like neuron specific RNA binding protein 2; ELAV like Neuronal Protein 1; ELAV like Protein 2; ELAV-like neuronal protein 1; ELAV-like protein 2; ELAV2_HUMAN; ELAVL2; HEL-N1; HELN1; HU Antigen B; Hu-antigen B; HuB; Nervous System Specific RNA Binding Protein MelN1; Nervous system-specific RNA-binding protein Hel-N1; ELAV (embryonic lethal abnormal vision Drosophila) like 4; ELAV L4; ELAV like 4; ELAV like protein 4; ELAV-like protein 4; ELAV4_HUMAN; Elavl4; Embryonic lethal abnormal vision Drosophila homolog of like 4; Hu antigen D; Hu-antigen D; HuD; Paraneoplastic encephalomyelitis antigen HuD; PNEM; ELAVL2 blocking peptide
Ordering
For Research Use Only!
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Applicable Applications for ELAVL2 blocking peptide
Blocking/Control
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ELAVL2 blocking peptide
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,504 Da
NCBI Official Full Name
ELAV-like protein 2 isoform b
NCBI Official Synonym Full Names
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
NCBI Official Symbol
ELAVL2
NCBI Official Synonym Symbols
HUB; HELN1; HEL-N1
NCBI Protein Information
ELAV-like protein 2; hu-antigen B; ELAV-like neuronal protein 1; nervous system-specific RNA-binding protein Hel-N1
UniProt Protein Name
ELAV-like protein 2
Protein Family
UniProt Gene Name
ELAVL2
UniProt Synonym Gene Names
HUB; HuB
UniProt Entry Name
ELAV2_HUMAN

NCBI Description

The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Uniprot Description

ELAVL2: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 9p21

Molecular Function: protein binding; mRNA 3'-UTR binding; nucleotide binding

Biological Process: regulation of transcription, DNA-dependent

Research Articles on ELAVL2

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Product Notes

The ELAVL2 elavl2 (Catalog #AAA9627682) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ELAV2/4 can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the ELAVL2 elavl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELAV2/4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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