Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

NGF-beta active protein

Mouse NGF-beta

Gene Names
Ngf; Ngfb
Reactivity
Mouse
Purity
> 98% by SDS-PAGE
Synonyms
NGF-beta; Mouse NGF-beta; Recombinant Murine NGF-beta; NGF-beta active protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE
Form/Format
Lyophilized
Sequence
SSTHPVFHMG EFSVCDSVSV WVGDKTTATD IKGKEVTVLA EVNINN SVFR QYFFETKCRA SNPVESGCRG IDSKHWNSYC TTTHTFVKAL T TDEKQAAWR FIRIDTACVC VLSRKATRRG
Sequence Length
241
Endotoxin Level
< 0.1 ng per ug of NGF-beta
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <= 1.0 ng/ml, corresponding to a specific activity of >= 1 x 106 units/mg.
Related Product Information for NGF-beta active protein
beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of murine beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.4 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
Product Categories/Family for NGF-beta active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13.4 kDa
NCBI Official Full Name
beta-nerve growth factor isoform B
NCBI Official Synonym Full Names
nerve growth factor
NCBI Official Symbol
Ngf
NCBI Official Synonym Symbols
Ngfb
NCBI Protein Information
beta-nerve growth factor; beta-NGF; nerve growth factor, beta
UniProt Protein Name
Beta-nerve growth factor
UniProt Gene Name
Ngf
UniProt Synonym Gene Names
Ngfb; Beta-NGF
UniProt Entry Name
NGF_MOUSE

Uniprot Description

Function: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.

Subunit structure: Homodimer.

Subcellular location: Secreted.

Sequence similarities: Belongs to the NGF-beta family.

Sequence caution: The sequence AAA37687.1 differs from that shown. Reason: Erroneous initiation. The sequence AAA39818.1 differs from that shown. Reason: Erroneous initiation. The sequence AAA39820.1 differs from that shown. Reason: Erroneous initiation. The sequence AAA39821.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA24221.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on NGF-beta

Similar Products

Product Notes

The NGF-beta ngf (Catalog #AAA691763) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse NGF-beta reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SSTHPVFHMG EFSVCDSVSV WVGDKTTATD IKGKEVTVLA EVNINN SVFR QYFFETKCRA SNPVESGCRG IDSKHWNSYC TTTHTFVKAL T TDEKQAAWR FIRIDTACVC VLSRKATRRG. It is sometimes possible for the material contained within the vial of "NGF-beta, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.