Human dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 3 ELISA Kit | DYRK3 elisa kit
Human Dual specificity tyrosine-phosphorylation-regulated kinase 3, DYRK3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
DYRK3: a dual-specificity protein kinase of the DYRK family. Localizes in the cytoplasm. Expressed primarily in erythroid progenitor cells and regulates late erythropoiesis.
Protein type: Kinase, protein; EC 2.7.12.1; Protein kinase, dual-specificity (non-receptor); Protein kinase, CMGC; CMGC group; DYRK family; Dyrk2 subfamily
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: nucleus
Molecular Function: protein serine/threonine kinase activity; protein-tyrosine kinase activity; protein serine/threonine/tyrosine kinase activity; magnesium ion binding; ATP binding; protein kinase activity
Biological Process: peptidyl-tyrosine phosphorylation; erythrocyte differentiation; protein amino acid phosphorylation
Research Articles on DYRK3
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Product Notes
The Human DYRK3 dyrk3 (Catalog #AAA9333025) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333025 ELISA Kit recognizes Human DYRK3. It is sometimes possible for the material contained within the vial of "dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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