Transcriptional activator DEMETER (DME) Recombinant Protein | DME recombinant protein
Recombinant Arabidopsis thaliana Transcriptional activator DEMETER (DME), partial
Gene Names
DME; AT5G04570; AT5G04580; DEMETER; T32M21.160; T32M21_160
Reactivity
Mouse-ear cress
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Transcriptional activator DEMETER (DME); Recombinant Arabidopsis thaliana Transcriptional activator DEMETER (DME); partial; DNA glycosylase-related protein DME; DME recombinant protein
Host
E Coli
Reactivity
Mouse-ear cress
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Sequence Positions
Partial, 1-320aa
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Related Product Information for DME recombinant protein
Transcriptional activator involved in gene imprinting. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism. Allows the expression of the maternal copy of the imprinted MEA gene before fertilization, possibly by antagonizing or suppressing DNA methylation on target promoter. Probably acts by nicking the MEA promoter. Required for stable reproducible patterns of floral and vegetative development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51.34 kDa
NCBI Official Full Name
HhH-GPD base excision DNA repair family protein
NCBI Official Symbol
DME
NCBI Official Synonym Symbols
AT5G04570; AT5G04580; DEMETER; T32M21.160; T32M21_160
NCBI Protein Information
HhH-GPD base excision DNA repair family protein
UniProt Protein Name
Transcriptional activator DEMETER
Protein Family
UniProt Gene Name
DME
NCBI Description
Encodes a DNA glycosylase DEMETER (DME). Responsible for endosperm maternal-allele-specific hypomethylation at the MEDEA (MEA) gene. DME can excise 5-methylcytosine in vitro and when expressed in E. coli. DME establishes MEA imprinting by removing 5-methylcytosine to activate the maternal allele.
Uniprot Description
Transcriptional activator involved in gene imprinting. Catalyzes the release of 5-methylcytosine (5-meC) from DNA by a glycosylase/lyase mechanism. Allows the expression of the maternal copy of the imprinted MEA gene before fertilization, possibly by antagonizing or suppressing DNA methylation on target promoter. Probably acts by nicking the MEA promoter. Required for stable reproducible patterns of floral and vegetative development.
Research Articles on DME
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Product Notes
The DME dme (Catalog #AAA9424083) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Partial, 1-320aa. The Recombinant Arabidopsis thaliana Transcriptional activator DEMETER (DME), partial reacts with Mouse-ear cress and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Transcriptional activator DEMETER (DME), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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