Single-stranded DNA-binding protein DdrA (ddrA) Recombinant Protein | ddrA recombinant protein
Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA (ddrA)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Single-stranded DNA-binding protein DdrA (ddrA); Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA (ddrA); Single-stranded DNA-binding protein DdrA; DNA damage response protein A; ddrA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-208aa; full length protein
Sequence
MKLSDVQKRL QAPFPAHTVS WKPAAFNAER TRALLLAHVD ARAVQDRLDA VCPDDWSFEMEVVSGAEVPT VKGRLTVLGV TREDIGEAPE GSMAAYKAAA SDAMKRCAVQ FGIGRYLYDLPKQWADWDDA RRGPKHLPEL PEWARPDHER TPGGAHLVQA MEQLRYELPE DLDLQREVYKHLKAALGSIH PVPTGPVPTN PVQGGRAA
Sequence Length
208
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,002 Da
NCBI Official Full Name
hypothetical protein DR_0423
NCBI Official Symbol
DR_0423
NCBI Protein Information
hypothetical protein
UniProt Protein Name
Single-stranded DNA-binding protein DdrA
Protein Family
UniProt Gene Name
ddrA
UniProt Entry Name
DDRA_DEIRA
Uniprot Description
ssDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Plays a role in DNA repair and genome reconstitution, in a RecA-independent process, since DdrA is essential for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation in an environment lacking nutrients. In vitro, binds to the 3'-ends of single-stranded DNA, protecting them from nuclease degradation. Thus, DdrA is part of a DNA end-protection system that helps to preserve genome integrity following irradiation or desiccation. Does not display DNA strand annealing activity, unlike eukaryotic Rad52 protein homologs.
Research Articles on ddrA
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Product Notes
The ddrA ddra (Catalog #AAA1396774) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-208aa; full length protein. The amino acid sequence is listed below: MKLSDVQKRL QAPFPAHTVS WKPAAFNAER TRALLLAHVD ARAVQDRLDA VCPDDWSFEM EVVSGAEVPT VKGRLTVLGV TREDIGEAPE GSMAAYKAAA SDAMKRCAVQ FGIGRYLYDL PKQWADWDDA RRGPKHLPEL PEWARPDHER TPGGAHLVQA MEQLRYELPE DLDLQREVYK HLKAALGSIH PVPTGPVPTN PVQGGRAA. It is sometimes possible for the material contained within the vial of "Single-stranded DNA-binding protein DdrA (ddrA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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