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Creatine transporter 1 / SLC6A8 Blocking Peptide | SLC6A8 blocking peptide

Creatine transporter 1 / SLC6A8 Immunizing Peptide

Gene Names
SLC6A8; CRT; CT1; CRTR; CTR5; CCDS1
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Synonyms
Creatine transporter 1 / SLC6A8; Creatine transporter 1 / SLC6A8 Immunizing Peptide; SLC6A8; solute carrier family 6 (neurotransmitter transporter; creatine); member 8; CRT; CRTR; CT1; MGC87396; creatine transporter 1; creatine transporter SLC6A8; sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 member 8; Creatine transporter 1; SLC6A8 blocking peptide
Ordering
 
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For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Sequence
ASLANLTCDQLADRR
Sequence Length
635
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
Molecular Weight
58,453 Da
NCBI Official Full Name
sodium- and chloride-dependent creatine transporter 1 isoform 1
NCBI Official Synonym Full Names
solute carrier family 6 member 8
NCBI Official Symbol
SLC6A8
NCBI Official Synonym Symbols
CRT; CT1; CRTR; CTR5; CCDS1
NCBI Protein Information
sodium- and chloride-dependent creatine transporter 1
UniProt Protein Name
Sodium- and chloride-dependent creatine transporter 1
UniProt Gene Name
SLC6A8
UniProt Synonym Gene Names
CT1; Creatine transporter 1
UniProt Entry Name
SC6A8_HUMAN

NCBI Description

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Uniprot Description

SLC6A8: Required for the uptake of creatine in muscles and brain. Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome (XL-CDS). XL-CDS causes developmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: creatine transporter activity; creatine:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: creatine metabolic process; creatine transport; muscle contraction; neurotransmitter transport; sodium ion transport; transport

Disease: Cerebral Creatine Deficiency Syndrome 1

Research Articles on SLC6A8

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Product Notes

The SLC6A8 slc6a8 (Catalog #AAA427584) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The Creatine transporter 1 / SLC6A8 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: ASLANLTCDQ LADRR. It is sometimes possible for the material contained within the vial of "Creatine transporter 1 / SLC6A8, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.
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