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Complement factor H-related protein 4 (CFHR4) Recombinant Protein | CFHR4 recombinant protein

Recombinant Human Complement factor H-related protein 4 (CFHR4)

Gene Names
CFHR4; FHR4; CFHL4; FHR-4
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Complement factor H-related protein 4 (CFHR4); Recombinant Human Complement factor H-related protein 4 (CFHR4); CFHR4 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
20-331, Full length protein
Sequence
EVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWSPTVPCLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGYNANTSVLSFQAVCREGIVEYPRCE
Sequence Length
312
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,299 Da
NCBI Official Full Name
complement factor H-related protein 4 isoform 1
NCBI Official Synonym Full Names
complement factor H related 4
NCBI Official Symbol
CFHR4
NCBI Official Synonym Symbols
FHR4; CFHL4; FHR-4
NCBI Protein Information
complement factor H-related protein 4
UniProt Protein Name
Complement factor H-related protein 4
UniProt Gene Name
CFHR4
UniProt Synonym Gene Names
CFHL4; FHR4; FHR-4

NCBI Description

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]

Uniprot Description

Involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.

Research Articles on CFHR4

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Product Notes

The CFHR4 cfhr4 (Catalog #AAA1279905) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-331, Full length protein. The amino acid sequence is listed below: EVKPCDFPEI QHGGLYYKSL RRLYFPAAAG QSYSYYCDQN FVTPSGSYWD YIHCTQDGWS PTVPCLRTCS KSDIEIENGF ISESSSIYIL NKEIQYKCKP GYATADGNSS GSITCLQNGW SAQPICIKFC DMPVFENSRA KSNGMRFKLH DTLDYECYDG YEISYGNTTG SIVCGEDGWS HFPTCYNSSE KCGPPPPISN GDTTSFLLKV YVPQSRVEYQ CQSYYELQGS NYVTCSNGEW SEPPRCIHPC IITEENMNKN NIQLKGKSDI KYYAKTGDTI EFMCKLGYNA NTSVLSFQAV CREGIVEYPR CE. It is sometimes possible for the material contained within the vial of "Complement factor H-related protein 4 (CFHR4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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