DYNC1LI1 cdna clone
DYNC1LI1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016]
Uniprot Description
DNCLI1: a cytoskeletal motor protein that is a subunit of cytoplasmic dynein. Possesses GTPase activity. Its function is regulated by phosphorylation. Cytoplasmic dynein is a minus-end-directed, microtubule-dependent motor composed of two heavy chains, three intermediate chains, and a family of light chains.
Protein type: Cytoskeletal; Microtubule-binding; Motility/polarity/chemotaxis; Cell cycle regulation; Motor
Chromosomal Location of Human Ortholog: 3p22.3
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; kinetochore; membrane; nucleoplasm; plasma membrane; spindle pole
Molecular Function: dynein heavy chain binding; GDP binding; GTP binding; protein binding
Research Articles on DYNC1LI1
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Product Notes
The DYNC1LI1 dync1li1 (Catalog #AAA1265824) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCGGCCG TGGGGCGAGT CGGCTCCTTC GGTTCTTCTC CGCCGGGATT ATCCTCGACT TACACTGGCG GCCCCTTGGG CAACGAGATA GCGTCGGGCA ACGGTGGCGC CGCGGCAGGC GACGACGAGG ACGGGCAGAA CCTTTGGTCC TGCATCCTCA GCGAGGTCTC CACCCGCTCG CGCTCCAAGC TCCCTGCGGG GAAGAACGTG CTACTGCTGG GTGAAGATGG AGCTGGAAAA ACAAGCTTAA TAAGAAAAAT TCAGGGAATA GAGGAGTATA AGAAAGGAAG AGGATTGGAA TATTTGTACT TAAATGTGCA TGATGAAGAC AGGGATGATC AAACAAGATG TAATGTTTGG ATCTTAGATG GAGACCTATA TCACAAAGGC CTCCTTAAAT TTTCACTGGA TGCCGTATCT CTGAAGGATA CTCTAGTTAT GCTGGTTGTT GACATGTCAA AGCCTTGGAC TGCTTTGGAT TCTTTACAGA AATGGGCAAG TGTTGTTAGA GAACATGTTG ACAAACTGAA AATCCCTCCT GAAGAAATGA AACAAATGGA ACAAAAGTTG ATTAGAGACT TCCAAGAATA TGTAGAGCCA GGAGAAGACT TCCCGGCTTC TCCCCAGAGA AGAAATACTG CGTCACAAGA AGACAAAGAT GACAGTGTAG TTTTACCTCT GGGTGCGGAT ACACTTACAC ATAACTTGGG CATTCCAGTA CTAGTAGTTT GCACAAAGTG TGATGCCATT AGTGTATTGG AGAAAGAACA TGACTACAGA GATGAACATT TTGATTTTAT TCAGTCACAT ATCCGGAAGT TTTGTTTACA GTATGGTGCA GCACTTATTT ACACTTCAGT AAAAGAAAAC AAAAATATAG ACTTAGTATA TAAATACATC GTTCAGAAAC TATATGGATT TCCCTATAAG ATTCCTGCTG TTGTTGTGGA AAAGGATGCA GTATTTATTC CAGCAGGGTG GGATAATGAT AAGAAAATAG GAATATTACA TGAAAATTTT CAAACATTAA AAGCAGAAGA TAATTTTGAA GACATCATAA CTAAACCACC TGTTCGAAAG TTTGTACATG AGAAGGAAAT TATGGCAGAA GATGATCAGG TGTTTCTTAT GAAGCTACAG TCCCTTTTAG CAAAGCAACC ACCAACTGCA GCTGGAAGGC CTGTGGATGC CTCACCAAGA GTCCCAGGAG GCTCCCCACG AACACCAAAT AGATCTGTAT CATCTAATGT TGCCAGCGTG TCACCCATTC CTGCTGGGTC AAAAAAAATT GATCCAAACA TGAAAGCTGG AGCTACAAGT GAAGGCGTTC TGGCAAATTT CTTCAACAGT TTGTTGAGTA AAAAGACTGG CTCTCCAGGA GGCCCTGGTG TGAGTGGTGG TAGCCCTGCA GGTGGGGCTG GAGGTGGAAG CAGTGGTTTA CCACCATCCA CCAAAAAGTC AGGCCAGAAG CCTGTCTTAG ATGTTCATGC AGAACTAGAC AGAATTACAC GAAAACCAGT TACAGTTTCT CCCACAACAC CTACATCTCC TACGGAAGGA GAAGCTTCTT GA. It is sometimes possible for the material contained within the vial of "DYNC1LI1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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