ADCY10 cdna clone
ADCY10 cDNA Clone
Gene Names
ADCY10; SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
Synonyms
ADCY10; ADCY10 cDNA Clone; ADCY10 cdna clone
Sequence
atgaacactccaaaagaagaattccaggactggcccatagtcagaatagcagctcatttaccagacctcattgtctatggacatttctccccagagcgaccctttatggattattttgacggagtcctgatgtttgttgatatttcaggttttactgcaatgactgagaagttcagcagtgccatgtacatggacagaggggctgagcagttggtggagatcctcaactaccacataagtgcaatagtggagaaagtgttgatttttggaggagacatcctgaaatttgcaggtgatgcactgctagccctgtggagggtggagcgaaagcagctgaaaaacattatcacagtggtaattaaatgtagcctggagatccatggattgtttgagacccaggagtgggaagaaggcctagacatccgagtcaagataggactggctgctggccacatcagcatgttggtctttggagatgaaacacacagccactttctggtgattggtcaggcagtggacgatgtgcgccttgcccagaacatggctcagatgaatgatgttattctgtcaccaaactgctggcagctctgtgaccggagcatgattgaaattgagagtgttccagatcagagagcagttaaggttaacttcttaaaaccaccccccaattttaattttgatgaatttttcacaaagtgtacgaccttcatgcattattatccttctggtgagcacaaaaacctcctgaggcttgcatgcacgctgaagcctgatcctgaactggagatgtccctacaaaagtatgtgatggaaagcattttgaagcagattgataacaaacagcttcagggctatttatctgagcttcgcccagtgacgattgtgtttgtgaacctgatgtttgaagaccaagacaaagcagaagagataggcccagccatccaggatgcctatatgcacatcacttctgtcctgaagatcttccaaggccaaatcaataaagtcttcatgtttgacaagggctgctctttcctctgtgtctttggcttccctggggaaaaggtacctgacgagctcactcatgctctggaatgtgctatggatatatttgacttctgctctcaagtccacaaaatccaaactgtatccatcggtgttgccagtgggattgtcttctgtgggatcgttggacacactgtgagacacgagtacacagtcattggtcaaaaagtcaacttagctgccaggatgatgatgtactacccaggaattgtgacctgcgactctgtcacctacaatgggagcaacctaccagcgtacttttttaaagagcttccaaagaaagttatgaaaggtgttgcagattctggaccattgtatcagtattggggccgtactgagaaagtcatgtttggtatggcgtgcctcatctgcaacagaaaggaggattaccctttgctgggacgtaataaagagatcaactacttcatgtatactatgaagaaatttttgatatctaacagcagccaagtcttaatgtatgagggattaccaggatatggaaaaagccagatacttatgaaaattgagtacctggcccaaggtaagaatcacaggattattgccatttcattgaataagatcagcttccatcaaactttctataccatccagatgttcatggccaatgtcctaggcctagacacttgtaaacattataaagaacgacagaccaaccttcgaaataaagtcatgacactgttggatgaaaagttctactgtcttcttaatgacattttccatgttcagttccctatttctcgggagatttccaggatgagcaccttgaaaaagcaaaaacaattggaaatattgtttatgaagatcttgaagctgatagtgaaagaggaaaggattatttttatcattgatgaggcccagtttgtggattcgacctcctggagatttatggagaagcttatccggactcttcctatcttcatcattatgtccctgtgtcccttcgttaacattccctgtgcagctgccagggccgtaataaagaacaggaacaccacctacattgtcattggtgcagtacagcctaacgacatctccaacaagatctgtcttgacctcaatgtgagctgcatctccaaagaactggactcgtacctgggggagggaagctgtgggattccattttactgtgaagaattgcttaaaaacctggaacatcatgaggtactcgttttccaacaaacggagtctgaggaaaagacaaataggacctggaataacctgttcaagtattccattaagctaacagagaagttaaacatggttactctccatagtgataaggaaagtgaagaagtctgtcacctcacaagtggcgtcagactgaaaaacctgtcacctccaacgtcattaaaagaaatctctctgatccagctggatagcatgagactttcccaccaaatgctggtgagatgtgctgccatcattggcctgaccttcaccactgagttgttgtttgagattctcccctgttggaatatgaagatgatgatcaagaccctggcaaccctagtggaatctaacattttttattgtttccggaatggcaaggagcttcaaaaggccctgaaacagaatgatccctcatttgaggtgcactatcgttccttgtctctgaagcccagtgaagggatggatcacggtgaagaggaacagcttcgtgaactggagaatgaggtgatcgagtgccacaggattcgattctgtaaccctatgatgcagaaaacagcctacgagctgtggctcaaggaccagagaaaagccatgcacttgaaatgtgcccgctttttagaagaagatgcccacagatgtgaccactgccgaggcagggacttcattccctatcatcacttcacagtgaatattcggctcaacgctttagacatggatgccattaaaaagatggctatgtctcatggatttaaaactgaagaaaagcttatcttgtccaactcagagattcctgagacatctgcattttttcctgaaaatcgcagtcctgaagaaataagagaaaagatcttgaatttctttgaccacgttttaacaaaaatgaagacatctgacgaagacattatccctctggaatcttgccagtgtgaagaaatcctagagattgtcatcttgcctctggcccaccattttctggctttgggagaaaatgacaaagccttatattacttcttagaaattgcatctgcttatctcatcttttgtgataactacatggcatacatgtatttgaatgaaggacagaagttgctaaaaactctcaagaaggacaaatcttggagccagacatttgagtctgccaccttttacagcctcaaaggtgaggtctgtttcaatatgggccagatagtgcttgccaagaaaatgctgaggaaggcactgaagctcctcaaccgaatctttccttacaacttaatctccttgtttctccatatccatgtcgagaaaaacagacactttcattatgtgaatcggcaggcccaagagagcccacctccagggaagaagaggctggcacaactttaccggcaaactgtctgcctttccttgctgtggcgcatctatagctacagttatctttttcactgcaagtattatgcccacctggcagttatgatgcaaatgaatactgcactggaaactcaaaattgtttccagatcattaaggcttacctagactattcgctataccaccacctggctggctacaaaggtgtgtggttcaaatatgaagtcatggccatggagcacatcttcaacctccccctgaaaggcgagggcattgaaatcgtggcatacgtggctgagacactggtcttcaacaagctcataatgggacacctggatttggccattgagttaggctcccgagcccttcagatgtgggcactgctccagaatcccaaccgacattatcagtccctctgcagacttagcagatgtctccttctgaacagcagatacccgcaattgatccaggtgctggggcggctgtgggagctttctgtaacacaggaacacatcttcagcaaggcatttttctattttgtctgcttggacatcctgctttattctggttttgtttatagaacatttgaagaatgtttggaattcatacaccaatacgaaaacaacagaatcctcaagttccacagtggactcctcctgggactttattcctctgtagctatctggtatgccagacttcaggaatgggacaacttttacaaattttccaatagagctaaaaatcttttgccaagaagaaccatgacacttacttactatgacggaatatctaggtacatggaggggcaagttcttcaccttcaaaaacaaatcaaagaacagtcagagaatgcccaagccagtggggaggagctactcaagaacttggagaatctggtggctcaaaataccactggccctgtcttttgcccaaggctctaccacctgatggcttacgtctgtatattaatgggagatgggcagaaatgtggcctcttcctgaacacagccttgcggctctctgaaacacaggggaatatactggagaaatgctggctgaacatgaacaaagaatcatggtactcaacctctgagttaaaagaagaccaatggcttcagacgatcttgagtctcccatcatgggaaaaaattgtagcaggcagggtaaacattcaggatcttcaaaaaaacaaattcctgatgagagctaataccgtggacaatcatttctaa
Sequence Length
4833
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
169,750 Da
NCBI Official Full Name
Homo sapiens adenylate cyclase 10 (soluble), mRNA
NCBI Official Synonym Full Names
adenylate cyclase 10, soluble
NCBI Official Symbol
ADCY10
NCBI Official Synonym Symbols
SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
NCBI Protein Information
adenylate cyclase type 10
UniProt Protein Name
Adenylate cyclase type 10
Protein Family
UniProt Gene Name
ADCY10
UniProt Synonym Gene Names
SAC; hsAC; sAC
UniProt Entry Name
ADCYA_HUMAN
NCBI Description
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]
Uniprot Description
SAC: Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation. Genetic variations in ADCY10 are a cause of susceptibility to hypercalciuria absorptive type 2 (HCA2). Absorptive hypercalciuria is a common type of hypercalciuria, a condition characterized by excessive urinary calcium excretion. Absorptive hypercalciuria is due to gastrointestinal hyperabsorption of calcium and is a frequent cause of calcium oxalate nephrolithiasis. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleotide Metabolism - purine; EC 4.6.1.1; Adenylyl cyclase; Lyase
Chromosomal Location of Human Ortholog: 1q24
Cellular Component: cytoplasm; microtubule cytoskeleton; nucleus; perinuclear region of cytoplasm
Molecular Function: adenylate cyclase activity
Biological Process: cAMP biosynthetic process
Disease: Hypercalciuria, Absorptive, 2
Research Articles on ADCY10
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Product Notes
The ADCY10 adcy10 (Catalog #AAA1274341) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaacactc caaaagaaga attccaggac tggcccatag tcagaatagc agctcattta ccagacctca ttgtctatgg acatttctcc ccagagcgac cctttatgga ttattttgac ggagtcctga tgtttgttga tatttcaggt tttactgcaa tgactgagaa gttcagcagt gccatgtaca tggacagagg ggctgagcag ttggtggaga tcctcaacta ccacataagt gcaatagtgg agaaagtgtt gatttttgga ggagacatcc tgaaatttgc aggtgatgca ctgctagccc tgtggagggt ggagcgaaag cagctgaaaa acattatcac agtggtaatt aaatgtagcc tggagatcca tggattgttt gagacccagg agtgggaaga aggcctagac atccgagtca agataggact ggctgctggc cacatcagca tgttggtctt tggagatgaa acacacagcc actttctggt gattggtcag gcagtggacg atgtgcgcct tgcccagaac atggctcaga tgaatgatgt tattctgtca ccaaactgct ggcagctctg tgaccggagc atgattgaaa ttgagagtgt tccagatcag agagcagtta aggttaactt cttaaaacca ccccccaatt ttaattttga tgaatttttc acaaagtgta cgaccttcat gcattattat ccttctggtg agcacaaaaa cctcctgagg cttgcatgca cgctgaagcc tgatcctgaa ctggagatgt ccctacaaaa gtatgtgatg gaaagcattt tgaagcagat tgataacaaa cagcttcagg gctatttatc tgagcttcgc ccagtgacga ttgtgtttgt gaacctgatg tttgaagacc aagacaaagc agaagagata ggcccagcca tccaggatgc ctatatgcac atcacttctg tcctgaagat cttccaaggc caaatcaata aagtcttcat gtttgacaag ggctgctctt tcctctgtgt ctttggcttc cctggggaaa aggtacctga cgagctcact catgctctgg aatgtgctat ggatatattt gacttctgct ctcaagtcca caaaatccaa actgtatcca tcggtgttgc cagtgggatt gtcttctgtg ggatcgttgg acacactgtg agacacgagt acacagtcat tggtcaaaaa gtcaacttag ctgccaggat gatgatgtac tacccaggaa ttgtgacctg cgactctgtc acctacaatg ggagcaacct accagcgtac ttttttaaag agcttccaaa gaaagttatg aaaggtgttg cagattctgg accattgtat cagtattggg gccgtactga gaaagtcatg tttggtatgg cgtgcctcat ctgcaacaga aaggaggatt accctttgct gggacgtaat aaagagatca actacttcat gtatactatg aagaaatttt tgatatctaa cagcagccaa gtcttaatgt atgagggatt accaggatat ggaaaaagcc agatacttat gaaaattgag tacctggccc aaggtaagaa tcacaggatt attgccattt cattgaataa gatcagcttc catcaaactt tctataccat ccagatgttc atggccaatg tcctaggcct agacacttgt aaacattata aagaacgaca gaccaacctt cgaaataaag tcatgacact gttggatgaa aagttctact gtcttcttaa tgacattttc catgttcagt tccctatttc tcgggagatt tccaggatga gcaccttgaa aaagcaaaaa caattggaaa tattgtttat gaagatcttg aagctgatag tgaaagagga aaggattatt tttatcattg atgaggccca gtttgtggat tcgacctcct ggagatttat ggagaagctt atccggactc ttcctatctt catcattatg tccctgtgtc ccttcgttaa cattccctgt gcagctgcca gggccgtaat aaagaacagg aacaccacct acattgtcat tggtgcagta cagcctaacg acatctccaa caagatctgt cttgacctca atgtgagctg catctccaaa gaactggact cgtacctggg ggagggaagc tgtgggattc cattttactg tgaagaattg cttaaaaacc tggaacatca tgaggtactc gttttccaac aaacggagtc tgaggaaaag acaaatagga cctggaataa cctgttcaag tattccatta agctaacaga gaagttaaac atggttactc tccatagtga taaggaaagt gaagaagtct gtcacctcac aagtggcgtc agactgaaaa acctgtcacc tccaacgtca ttaaaagaaa tctctctgat ccagctggat agcatgagac tttcccacca aatgctggtg agatgtgctg ccatcattgg cctgaccttc accactgagt tgttgtttga gattctcccc tgttggaata tgaagatgat gatcaagacc ctggcaaccc tagtggaatc taacattttt tattgtttcc ggaatggcaa ggagcttcaa aaggccctga aacagaatga tccctcattt gaggtgcact atcgttcctt gtctctgaag cccagtgaag ggatggatca cggtgaagag gaacagcttc gtgaactgga gaatgaggtg atcgagtgcc acaggattcg attctgtaac cctatgatgc agaaaacagc ctacgagctg tggctcaagg accagagaaa agccatgcac ttgaaatgtg cccgcttttt agaagaagat gcccacagat gtgaccactg ccgaggcagg gacttcattc cctatcatca cttcacagtg aatattcggc tcaacgcttt agacatggat gccattaaaa agatggctat gtctcatgga tttaaaactg aagaaaagct tatcttgtcc aactcagaga ttcctgagac atctgcattt tttcctgaaa atcgcagtcc tgaagaaata agagaaaaga tcttgaattt ctttgaccac gttttaacaa aaatgaagac atctgacgaa gacattatcc ctctggaatc ttgccagtgt gaagaaatcc tagagattgt catcttgcct ctggcccacc attttctggc tttgggagaa aatgacaaag ccttatatta cttcttagaa attgcatctg cttatctcat cttttgtgat aactacatgg catacatgta tttgaatgaa ggacagaagt tgctaaaaac tctcaagaag gacaaatctt ggagccagac atttgagtct gccacctttt acagcctcaa aggtgaggtc tgtttcaata tgggccagat agtgcttgcc aagaaaatgc tgaggaaggc actgaagctc ctcaaccgaa tctttcctta caacttaatc tccttgtttc tccatatcca tgtcgagaaa aacagacact ttcattatgt gaatcggcag gcccaagaga gcccacctcc agggaagaag aggctggcac aactttaccg gcaaactgtc tgcctttcct tgctgtggcg catctatagc tacagttatc tttttcactg caagtattat gcccacctgg cagttatgat gcaaatgaat actgcactgg aaactcaaaa ttgtttccag atcattaagg cttacctaga ctattcgcta taccaccacc tggctggcta caaaggtgtg tggttcaaat atgaagtcat ggccatggag cacatcttca acctccccct gaaaggcgag ggcattgaaa tcgtggcata cgtggctgag acactggtct tcaacaagct cataatggga cacctggatt tggccattga gttaggctcc cgagcccttc agatgtgggc actgctccag aatcccaacc gacattatca gtccctctgc agacttagca gatgtctcct tctgaacagc agatacccgc aattgatcca ggtgctgggg cggctgtggg agctttctgt aacacaggaa cacatcttca gcaaggcatt tttctatttt gtctgcttgg acatcctgct ttattctggt tttgtttata gaacatttga agaatgtttg gaattcatac accaatacga aaacaacaga atcctcaagt tccacagtgg actcctcctg ggactttatt cctctgtagc tatctggtat gccagacttc aggaatggga caacttttac aaattttcca atagagctaa aaatcttttg ccaagaagaa ccatgacact tacttactat gacggaatat ctaggtacat ggaggggcaa gttcttcacc ttcaaaaaca aatcaaagaa cagtcagaga atgcccaagc cagtggggag gagctactca agaacttgga gaatctggtg gctcaaaata ccactggccc tgtcttttgc ccaaggctct accacctgat ggcttacgtc tgtatattaa tgggagatgg gcagaaatgt ggcctcttcc tgaacacagc cttgcggctc tctgaaacac aggggaatat actggagaaa tgctggctga acatgaacaa agaatcatgg tactcaacct ctgagttaaa agaagaccaa tggcttcaga cgatcttgag tctcccatca tgggaaaaaa ttgtagcagg cagggtaaac attcaggatc ttcaaaaaaa caaattcctg atgagagcta ataccgtgga caatcatttc taa. It is sometimes possible for the material contained within the vial of "ADCY10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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