NCBI Description
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008]
Uniprot Description
RMI2: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM. Belongs to the RMI2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA replication
Chromosomal Location of Human Ortholog: 16p13.13
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding
Biological Process: DNA replication
Product Notes
The Human C16orf75 rmi2 (Catalog #
AAA9333941) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333941 ELISA Kit recognizes Human C16orf75.
It is sometimes possible for the material contained within the vial of
"chromosome 16 open reading frame 75, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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and its authorized distribution partners reserve the right to refuse to fulfill any order if
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purchaser may be intending to use a product outside of our accepted criteria.
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