V-type proton ATPase 16 kDa proteolipid subunit (ATP6V0C) Recombinant Protein | ATP6V0C recombinant protein
Recombinant Bovine V-type proton ATPase 16 kDa proteolipid subunit (ATP6V0C)
NCBI and Uniprot Product Information
Uniprot Description
Function: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit structure: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein; which is present as a hexamer that forms the proton-conducting pore). Interacts with LASS2
By similarity. Interacts with RNF182; this interaction leads to ubiquitination and degradation via the proteasome pathway
By similarity.
Subcellular location: Vacuole membrane; Multi-pass membrane protein.
Post-translational modification: Ubiquitinated by RNF182, leading to its degradation via the ubiquitin-proteasome pathway
By similarity.
Sequence similarities: Belongs to the V-ATPase proteolipid subunit family.
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Product Notes
The ATP6V0C atp6v0c (Catalog #AAA959438) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-155. The amino acid sequence is listed below: MSEAKNGPEY ASFFAVMGAS AAMVFSALGA AYGTAKSGTG IAAMSVMRPE MIMKSIIPVV MAGIIAIYGL VVAVLIANSL NDGISLYRSF LQLGAGLSVG LSGLAAGFAI GIVGDAGVRG TAQQPRLFVG MILILIFAEV LGLYGLIVAL ILSTK. It is sometimes possible for the material contained within the vial of "V-type proton ATPase 16 kDa proteolipid subunit (ATP6V0C), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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